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. 1987 Feb;205(2):144–150. doi: 10.1097/00000658-198702000-00008

Malignant lymphoma of the breast. A study of 53 patients.

S Brustein, D A Filippa, M Kimmel, P H Lieberman, P P Rosen
PMCID: PMC1492821  PMID: 3545107

Abstract

Fifty-three patients with non-Hodgkin's lymphoma of the breast were reviewed and classified using four current classifications of lymphoma. All patients were female with a mean age of 57 years. The majority of patients had histiocytic or large-cell lesions and presented as clinical Stage I. The tumors were described clinically as primary in the breast, and mammary parenchyma was found in 79% of the diagnostic biopsy specimens. The other specimens showed lymphoma in mammary adipose tissue. Survival was not influenced by the presence or absence of breast parenchyma in the biopsy. Statistically significant survival differences were found to be related to stage at presentation as well as to tumor grade, using Kiel and Working Formulation categories. Patients with Stage I disease and those with low-grade lesions had a more favorable prognosis. No discernible factors, including stage or histologic findings, appeared to affect the recurrence rate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alm P., Brandt L., Olsson H. Immunoglobulin-A producing probably primary lymphoma of the breast. Virchows Arch A Pathol Anat Histopathol. 1983;399(3):355–360. doi: 10.1007/BF00612953. [DOI] [PubMed] [Google Scholar]
  2. Carbone A., Volpe R., Tirelli U., Veronesi A., Galligioni E., Trovo M. G., Grigoletto E. Primary lymphoblastic lymphoma of the breast. Clin Oncol. 1982 Dec;8(4):367–373. [PubMed] [Google Scholar]
  3. DECOSSE J. J., BERG J. W., FRACCHIA A. A., FARROW J. H. Primary lymphosarcoma of the breast. A review of 14 cases. Cancer. 1962 Nov-Dec;15:1264–1268. doi: 10.1002/1097-0142(196211/12)15:6<1264::aid-cncr2820150623>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
  4. Dworkin B., Lightdale C. J., Weingrad D. N., DeCosse J. J., Lieberman P., Filippa D. A., Sherlock P., Straus D. Primary gastric lymphoma. A review of 50 cases. Dig Dis Sci. 1982 Nov;27(11):986–992. doi: 10.1007/BF01391744. [DOI] [PubMed] [Google Scholar]
  5. Filippa D. A., Lieberman P. H., Weingrad D. N., Decosse J. J., Bretsky S. S. Primary lymphomas of the gastrointestinal tract. Analysis of prognostic factors with emphasis on histological type. Am J Surg Pathol. 1983 Jun;7(4):363–372. doi: 10.1097/00000478-198306000-00008. [DOI] [PubMed] [Google Scholar]
  6. Freedman S. I., Kagan A. R., Friedman N. B. Bilaterality in primary lymphosarcoma of the breast. Am J Clin Pathol. 1971 Jan;55(1):82–87. doi: 10.1093/ajcp/55.1.82. [DOI] [PubMed] [Google Scholar]
  7. L'Hoste R. J., Jr, Filippa D. A., Lieberman P. H., Bretsky S. Primary pulmonary lymphomas. A clinicopathologic analysis of 36 cases. Cancer. 1984 Oct 1;54(7):1397–1406. doi: 10.1002/1097-0142(19841001)54:7<1397::aid-cncr2820540728>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]
  8. Mambo N. C., Burke J. S., Butler J. J. Primary malignant lymphomas of the breast. Cancer. 1977 May;39(5):2033–2040. doi: 10.1002/1097-0142(197705)39:5<2033::aid-cncr2820390520>3.0.co;2-v. [DOI] [PubMed] [Google Scholar]
  9. Rosen P. P., Lesser M. L., Senie R. T., Duthie K. Epidemiology of breast carcinoma IV: age and histologic tumor type. J Surg Oncol. 1982 Jan;19(1):44–51. doi: 10.1002/jso.2930190112. [DOI] [PubMed] [Google Scholar]
  10. Rudders R. A., Ross M. E., DeLellis R. A. Primary extranodal lymphoma: response to treatment and factors influencing prognosis. Cancer. 1978 Aug;42(2):406–416. doi: 10.1002/1097-0142(197808)42:2<406::aid-cncr2820420205>3.0.co;2-h. [DOI] [PubMed] [Google Scholar]
  11. Schouten J. T., Weese J. L., Carbone P. P. Lymphoma of the breast. Ann Surg. 1981 Dec;194(6):749–753. doi: 10.1097/00000658-198112000-00015. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Senie R. T., Rosen P. P., Lesser M. L., Snyder R. E., Schottenfeld D., Duthie K. Epidemiology of breast carcinoma II: factors related to the predominance of left-sided disease. Cancer. 1980 Oct 1;46(7):1705–1713. doi: 10.1002/1097-0142(19801001)46:7<1705::aid-cncr2820460734>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
  13. Sonnenblick M., Abraham A. S. Primary lymphosarcoma of the breast: review of the literature on occurrence in elderly patients. J Am Geriatr Soc. 1976 May;24(5):225–227. doi: 10.1111/j.1532-5415.1976.tb06783.x. [DOI] [PubMed] [Google Scholar]
  14. Tanaka T., Hsueh C. L., Hayashi K., Awai M., Nishihara K., Konaga E., Ichikawa J., Orita K. Primary malignant lymphoma of the breast. With a review of 73 cases among Japanese subjects. Acta Pathol Jpn. 1984 Mar;34(2):361–373. doi: 10.1111/j.1440-1827.1984.tb07564.x. [DOI] [PubMed] [Google Scholar]
  15. Wenner S. M., Fineberg C. Case report; primary lymphosarcoma of the breast. Pa Med. 1979 Apr;82(4):39–41. [PubMed] [Google Scholar]
  16. Wiseman C., Liao K. T. Primary lymphoma of the breast. Cancer. 1972 Jun;29(6):1705–1712. doi: 10.1002/1097-0142(197206)29:6<1705::aid-cncr2820290640>3.0.co;2-i. [DOI] [PubMed] [Google Scholar]
  17. Yoshida Y. Reticulum cell sarcoma of the breast. Case report and a review of the Japanese literature. Cancer. 1970 Jul;26(1):94–99. doi: 10.1002/1097-0142(197007)26:1<94::aid-cncr2820260111>3.0.co;2-w. [DOI] [PubMed] [Google Scholar]
  18. de Souza L. J., Talvalkar G. V., Morjaria J. H. Primary malignant lymphoma of the breast. Indian J Cancer. 1978 Dec;15(4):30–35. [PubMed] [Google Scholar]

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