Abstract
The use of a nonparametric estimate from incomplete observations is demonstrated on ulcer recurrence 10-15 years after parietal cell vagotomy in 339 patients with duodenal ulcer. The median period of observation was 108 months (range: 1-197 months). Proven recurrent ulcer developed in 62 patients. The life-table method as described by Kaplan and Meier and Nelson's modification are demonstrated. The calculated risk of recurrence after 10 years was 23% (+/- 3.8%) and after 15 years was 27% (+/- 4.3%). The rate of recurrence seemed to decline toward the end of the trial time.
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- Amdrup E., Jensen H. E. Selective vagotomy of the parietal cell mass preserving innervation of the undrained antrum. A preliminary report of results in patients with duodenal ulcer. Gastroenterology. 1970 Oct;59(4):522–527. [PubMed] [Google Scholar]
- Jensen H. E., Kjaergaard J., Meisner S. Ulcer recurrence two to twelve years after parietal cell vagotomy for duodenal ulcer. Surgery. 1983 Nov;94(5):802–806. [PubMed] [Google Scholar]
- Johnston D., Wilkinson A. Selective vagotomy with innervated antrum without drainage procedure for duodenal ulcer. Br J Surg. 1969 Aug;56(8):626–626. [PubMed] [Google Scholar]
- Peto R., Pike M. C., Armitage P., Breslow N. E., Cox D. R., Howard S. V., Mantel N., McPherson K., Peto J., Smith P. G. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design. Br J Cancer. 1976 Dec;34(6):585–612. doi: 10.1038/bjc.1976.220. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Peto R., Pike M. C., Armitage P., Breslow N. E., Cox D. R., Howard S. V., Mantel N., McPherson K., Peto J., Smith P. G. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples. Br J Cancer. 1977 Jan;35(1):1–39. doi: 10.1038/bjc.1977.1. [DOI] [PMC free article] [PubMed] [Google Scholar]