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. 1988 Oct;208(4):410–420. doi: 10.1097/00000658-198810000-00003

Liver transplantation, including the concept of reduced-size liver transplants in children.

C E Broelsch 1, J C Emond 1, J R Thistlethwaite 1, P F Whitington 1, A R Zucker 1, A L Baker 1, P F Aran 1, D A Rouch 1, J L Lichtor 1
PMCID: PMC1493747  PMID: 3052326

Abstract

Since the establishment of a clinical program in liver transplantation in 1984, 162 liver transplants have been performed in 131 patients (78 adults, 53 children). The patient mortality rate while waiting for a suitable organ has been 8% for adults and only 4% for children (25-46% reported in the literature). The low pediatric mortality is a result of the use of reduced-size liver transplants. A total of 14 procedures have been performed in recipients whose clinical condition was deteriorating and for whom no full-size graft could be located. Of 14 children, 13 were less than 3 years of age. Patient survival is 50%, comparable to survival of high-risk recipients of full-size livers. Using reduced-size liver grafting in a transplant program can lower mortality for children awaiting a transplant by overcoming size disparity. Reduced-size liver grafting will allow more effective use of donor resources and provide a potential avenue of research for organ splitting and living related donation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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