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Canadian Journal of Comparative Medicine and Veterinary Science logoLink to Canadian Journal of Comparative Medicine and Veterinary Science
. 1966 Jul;30(7):199–203.

Studies of Escherichia coli in Gnotobiotic Pigs

I. Experimental Reproduction of Colibacillosis*

Erwin M Kohler, Edward H Bohl
PMCID: PMC1494551  PMID: 4224293

Abstract

The successful experimental production of colibacillosis in young gnotobiotic pigs by the oral administration of E. COLI (08:K.:H21 was accomplished. Colibacillosis was not produced in gnotobiotic pigs infected with either of the 2 other strains of E.COLI employed.

Necropsy observations were presented and discussed. Emphasis was placed on the absence of grossly visible enteritis in pigs that died in the acute phase of the disease. The gross appearance of the intestinal tract changed some hours after death to resemble that associated with enteritis.

Bacteremia was detected in the gnotobiotic pigs orally infected with each of the 3 strains of E. COLI, and the special characteristics of the colostrum-deprived pig were stressed as important factors in these findings.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BORTREE A. L., DUNNE H. W., GLANTZ P. J., HOKANSON J. F. Escherichia coli as a cause of diarrhea in calves. Ann N Y Acad Sci. 1956 Aug 10;66(1):129–135. doi: 10.1111/j.1749-6632.1956.tb40111.x. [DOI] [PubMed] [Google Scholar]
  2. COOPER M. L., KELLER H. M., WALTERS E. W. Escherichia coli associated with infantile diarrhea. Ann N Y Acad Sci. 1956 Aug 10;66(1):78–89. doi: 10.1111/j.1749-6632.1956.tb40105.x. [DOI] [PubMed] [Google Scholar]
  3. Dunne H. W. An Expanding Concept Of Colibacillosis With Emphasis On The Disease In Swine. Can J Comp Med Vet Sci. 1959 Mar;23(3):101–104. [PMC free article] [PubMed] [Google Scholar]
  4. GAY C. C. ESCHERICHIA COLI AND NEONATAL DISEASE OF CALVES. Bacteriol Rev. 1965 Mar;29:75–101. doi: 10.1128/br.29.1.75-101.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. LECCE J. G., REEP B. R. Escherichia coli associated with colostrum-free neonatal pigs raised in isolation. J Exp Med. 1962 Mar 1;115:491–501. doi: 10.1084/jem.115.3.491. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. MEYER R. C., BOHL E. H., KOHLER E. M. PROCUREMENT AND MAINTENANCE OF GERM-FREE SEINE FOR MICROBIOLOGICAL INVESTIGATIONS. Appl Microbiol. 1964 Jul;12:295–300. doi: 10.1128/am.12.4.295-300.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Rice C. E., L'ecuyer C. Complement Titres of Naturally and Artificially Raised Piglets: I. In piglets of different birth weights. Can J Comp Med Vet Sci. 1963 Jul;27(7):157–161. [PMC free article] [PubMed] [Google Scholar]
  8. SMITH H. W., JONES J. E. OBSERVATIONS ON THE ALIMENTARY TRACT AND ITS BACTERIAL FLORA IN HEALTHY AND DISEASED PIGS. J Pathol Bacteriol. 1963 Oct;86:387–412. [PubMed] [Google Scholar]
  9. WHEELER W. E. Spread and control of Escherichia coli diarrheal disease. Ann N Y Acad Sci. 1956 Aug 10;66(1):112–117. doi: 10.1111/j.1749-6632.1956.tb40109.x. [DOI] [PubMed] [Google Scholar]

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