Abstract
Electrophoretic examinations using cellulose acetate strips were made on 17 serum samples collected at two-week intervals from each of three calves before and for about four months after they were placed on parasite-infected pastures in June, 1964. Four additional serum samples taken during the winter months when the animals were stabled and two obtained after they were again exposed to infected pastures in June 1965, were also examined. Two control animals of the same age, that were placed on clean pasture in 1964 and not exposed to infected pasture until June 1965, were bled on the same dates and their sera examined in parallel. All five calves showed an increase in the proportion and amount of γ-globulin in their serum as they increased in age but the gain was greatest in the two exposed calves that developed the highest complement-fixing titres with nematode antigens. Complement-fixing titres rose slowly in the other exposed calf and its serum γ-globulin level remained relatively comparable to that of the two controls.
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Selected References
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- COCHRANE D., RICE C. E., CARRIERE J. STUDIES OF JOHNE'S DISEASE IN CANADA. XII. ELECTROPHORETIC ANALYSIS OF CHANGES IN SERUM PROTEINS IN INFECTED CATTLE AND SHEEP. Can J Comp Med Vet Sci. 1965 Aug;29:209–213. [PMC free article] [PubMed] [Google Scholar]
- HERLICH H., MERKAL R. S. SEROLOGICAL AND IMMUNOLOGICAL RESPONSES OF CALVES TO INFECTION WITH TRICHOSTRONGYLUS AXEI. J Parasitol. 1963 Aug;49:623–627. [PubMed] [Google Scholar]
- HERLICH H. Studies on calves experimentally infected with combinations of four nematode species. Am J Vet Res. 1962 May;23:521–528. [PubMed] [Google Scholar]
- LELAND S. E., Jr, DRUDGE J. H., WYANT Z. N. Studies on Trichostrongylus axel (Cobbold, 1879). III. Blood and plasma volume, total serum protein, and electrophoretic serum fractionation in infected and uninfected calves. Exp Parasitol. 1959 Aug;8:383–412. doi: 10.1016/0014-4894(59)90031-1. [DOI] [PubMed] [Google Scholar]
- MAHRT J. L., HAMMOND D. M., MINER M. L. CHANGES IN SERUM PROTEINS AND OTHER BLOOD VALUES ASSOCIATED WITH EXPERIMENTAL OSTERTAGIA OSTERTAGI INFECTIONS IN CALVES. Cornell Vet. 1964 Jul;54:453–474. [PubMed] [Google Scholar]
- ROSS J. G. Association of detectable antibodies produced by Haemonchus spp. infections in cattle, with serum globulin fractions. Nature. 1961 Jun 10;190:1019–1020. doi: 10.1038/1901019b0. [DOI] [PubMed] [Google Scholar]
- ROSS J. G., TODD J. R. BIOCHEMICAL, SEROLOGICAL AND HAEMATOLOGICAL CHANGES ASSOCIATED WITH INFECTIONS OF CALVES WITH THE NEMATODE PARASITE, OSTERTAGIA OSTERTAGI. Br Vet J. 1965 Feb;121:55–64. doi: 10.1016/s0007-1935(17)41351-0. [DOI] [PubMed] [Google Scholar]
- Rice C. E., Smith H. J. Serological studies of parasitized cattle. I. Complement--fixing activity of serial serum samples. Can J Comp Med Vet Sci. 1966 Sep;30(9):245–250. [PMC free article] [PubMed] [Google Scholar]
- SELL S., FAHEY J. L. RELATIONSHIP BETWEEN GAMMA-GLOBULIN METABOLISM AND LOW SERUM GAMMA-GLOBULIN IN GERMFREE MICE. J Immunol. 1964 Jul;93:81–87. [PubMed] [Google Scholar]
- SELL S. IMMUNOGLOBULINS OF THE GERMFREE GUINEA PIG. J Immunol. 1964 Jul;93:122–131. [PubMed] [Google Scholar]