Abstract
Geographical variations in specific causes of mortality among the 1366 local authority areas of England and Wales as defined at 1971 were studied by examining extracts from death certificates held on computer tape. Five items of information on each death--year of death, age at death, sex, local authority area of residence, and the underlying cause of death, during the 11 years 1968-78--permitted a more detailed investigation than had been possible before. Analysis of some early results of the study--including maps of mortality for pleural mesothelioma, nasal cancer and bladder cancer--suggested that, despite the known limitations of death certification, systematic study of the mortality of small areas may give clues to aetiological factors in the environment. Analyses relating mortality to the distribution of environmental factors and examining disease profiles of each area may also provide clues. These will be followed up by other methods of study, such as case-control techniques.
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Selected References
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- Acheson E. D., Cowdell R. H., Hadfield E., Macbeth R. G. Nasal cancer in woodworkers in the furniture industry. Br Med J. 1968 Jun 8;2(5605):587–596. doi: 10.1136/bmj.2.5605.587. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Acheson E. D., Cowdell R. H., Jolles B. Nasal cancer in the Northamptonshire boot and shoe industry. Br Med J. 1970 Feb 14;1(5693):385–393. doi: 10.1136/bmj.1.5693.385. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Acheson E. D., Cowdell R. H., Rang E. H. Nasal cancer in England and Wales: an occupational survey. Br J Ind Med. 1981 Aug;38(3):218–224. doi: 10.1136/oem.38.3.218. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Adelstein A. M. Current vital statistics: methods and interpretation. Br Med J. 1978 Oct 7;2(6143):983–987. doi: 10.1136/bmj.2.6143.983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Barker D. J. Geographical variations in disease in Britain. Br Med J (Clin Res Ed) 1981 Aug 8;283(6288):398–400. doi: 10.1136/bmj.283.6288.398. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Blot W. J., Fraumeni J. F., Jr Geographic patterns of oral cancer in the United States: etilogic implications. J Chronic Dis. 1977 Nov;30(11):745–757. doi: 10.1016/0021-9681(77)90003-0. [DOI] [PubMed] [Google Scholar]
- Blot W. J., Fraumeni J. F., Jr, Mason T. J., Hoover R. N. Developing clues to environmental cancer: a stepwise approach with the use of cancer mortality data. Environ Health Perspect. 1979 Oct;32:53–58. doi: 10.1289/ehp.793253. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gardner M. J., Crawford M. D., Morris J. N. Patterns of mortality in middle and early old age in the county boroughs of England and Wales. Br J Prev Soc Med. 1969 Aug;23(3):133–140. doi: 10.1136/jech.23.3.133. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Greenberg M., Davies T. A. Mesothelioma register 1967-68. Br J Ind Med. 1974 Apr;31(2):91–104. doi: 10.1136/oem.31.2.91. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Järvholm B., Lillienberg L., Sällsten G., Thiringer G., Axelson O. Cancer morbidity among men exposed to oil mist in the metal industry. J Occup Med. 1981 May;23(5):333–337. [PubMed] [Google Scholar]
- MACBETH R. MALIGNANT DISEASE OF THE PARANASAL SINUSES. J Laryngol Otol. 1965 Jul;79:592–612. doi: 10.1017/s0022215100064112. [DOI] [PubMed] [Google Scholar]
- Newhouse M. L., Berry G. Patterns of mortality in asbestos factory workers in London. Ann N Y Acad Sci. 1979;330:53–60. doi: 10.1111/j.1749-6632.1979.tb18709.x. [DOI] [PubMed] [Google Scholar]
- Newhouse M. L., Berry G., Wagner J. C., Turok M. E. A study of the mortality of female asbestos workers. Br J Ind Med. 1972 Apr;29(2):134–141. doi: 10.1136/oem.29.2.134. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wagner J. C., Gilson J. C., Berry G., Timbrell V. Epidemiology of asbestos cancers. Br Med Bull. 1971 Jan;27(1):71–76. doi: 10.1093/oxfordjournals.bmb.a070818. [DOI] [PubMed] [Google Scholar]
