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British Medical Journal (Clinical Research Ed.) logoLink to British Medical Journal (Clinical Research Ed.)
. 1982 Apr 24;284(6324):1226–1228. doi: 10.1136/bmj.284.6324.1226

Objective test for food sensitivity in asthmatic children: increased bronchial reactivity after cola drinks.

N Wilson, H Vickers, G Taylor, M silverman
PMCID: PMC1498055  PMID: 6803911

Abstract

Ten asthmatic children with a history of cough and wheeze after drinking a cola drink performed histamine inhalation tests before and 30 minutes after a drink of Pepsi-Cola, soda water, and water on three separate study days. There was no significant change in baseline peak expiratory flow after any of the three drinks. Sensitivity to histamine was increased after the cola drink (p less than 0.005) but was not significantly different after soda water or water. The detection of change in sensitivity to histamine appears to be a simple and effective method of testing for food sensitivity in asthma.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cockcroft D. W., Killian D. N., Mellon J. J., Hargreave F. E. Bronchial reactivity to inhaled histamine: a method and clinical survey. Clin Allergy. 1977 May;7(3):235–243. doi: 10.1111/j.1365-2222.1977.tb01448.x. [DOI] [PubMed] [Google Scholar]
  2. Cockcroft D. W., Ruffin R. E., Dolovich J., Hargreave F. E. Allergen-induced increase in non-allergic bronchial reactivity. Clin Allergy. 1977 Nov;7(6):503–513. doi: 10.1111/j.1365-2222.1977.tb01481.x. [DOI] [PubMed] [Google Scholar]
  3. Freedman B. J. Asthma induced by sulphur dioxide, benzoate and tartrazine contained in orange drinks. Clin Allergy. 1977 Sep;7(5):407–415. doi: 10.1111/j.1365-2222.1977.tb01471.x. [DOI] [PubMed] [Google Scholar]
  4. Galant S. P., Bullock J., Frick O. L. An immunological approach to the diagnosis of food sensitivity. Clin Allergy. 1973 Dec;3(4):363–372. doi: 10.1111/j.1365-2222.1973.tb01343.x. [DOI] [PubMed] [Google Scholar]
  5. Ruffin R. E., Alpers J. H., Crockett A. J., Hamilton R. Repeated histamine inhalation tests in asthmatic patients. J Allergy Clin Immunol. 1981 Apr;67(4):285–289. doi: 10.1016/0091-6749(81)90023-3. [DOI] [PubMed] [Google Scholar]

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