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. 1982 Aug 14;285(6340):467–468. doi: 10.1136/bmj.285.6340.467

Septicaemia due to Yersinia enterocolitica after oral overdoses of iron.

K Melby, S Slørdahl, T J Gutteberg, S A Nordbø
PMCID: PMC1499267  PMID: 6809127

Abstract

Septicaemia occurred after accidental oral overdoses of iron in two previously healthy children. Yersinia enterocolitica serotype 0:3 was recovered from blood and stool cultures in both patients. Enhanced growth of Y enterocolitica in the intestine combined with damage of intestinal mucosa may have been of major importance for the development of generalised infection in these cases. Iron and the iron chelating agent desferrioxamine may possibly have a pathogenetic role in such circumstances.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barry D. M., Reeve A. W. Increased incidence of gram-negative neonatal sepsis with intramuscula iron administration. Pediatrics. 1977 Dec;60(6):908–912. [PubMed] [Google Scholar]
  2. Bottone E. J. Yersinia enterocolitica: a panoramic view of a charismatic microorganism. CRC Crit Rev Microbiol. 1977;5(2):211–241. doi: 10.3109/10408417709102312. [DOI] [PubMed] [Google Scholar]
  3. Butzler J. P., Alexander M., Segers A., Cremer N., Wauters G. Enteritis, abscess and septicaemia by Yersinia enterocolitica in a thalassaemic child. Contrib Microbiol Immunol. 1979;5:292–297. [PubMed] [Google Scholar]
  4. Greengard J. Iron poisoning in children. Clin Toxicol. 1975;8(6):575–597. doi: 10.3109/15563657508990084. [DOI] [PubMed] [Google Scholar]
  5. Murray M. J., Murray A. B., Murray M. B., Murray C. J. The adverse effect of iron repletion on the course of certain infections. Br Med J. 1978 Oct 21;2(6145):1113–1115. doi: 10.1136/bmj.2.6145.1113. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Pai C. H., Mors V. Production of enterotoxin by Yersinia enterocolitica. Infect Immun. 1978 Mar;19(3):908–911. doi: 10.1128/iai.19.3.908-911.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Perry R. D., Brubaker R. R. Accumulation of iron by yersiniae. J Bacteriol. 1979 Mar;137(3):1290–1298. doi: 10.1128/jb.137.3.1290-1298.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Rabson A. R., Hallett A. F., Koornhof H. J. Generalized Yersinia enterocolitica infection. J Infect Dis. 1975 Apr;131(4):447–451. doi: 10.1093/infdis/131.4.447. [DOI] [PubMed] [Google Scholar]
  9. Robins-Browne R. M., Rabson A. R., Koornhof H. J. Generalized infection with Yersinia enterocolitica and the role of iron. Contrib Microbiol Immunol. 1979;5:277–282. [PubMed] [Google Scholar]
  10. Weinberg E. D. Iron and infection. Microbiol Rev. 1978 Mar;42(1):45–66. doi: 10.1128/mr.42.1.45-66.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Westlin W. F. Deferoxamine in the treatment of acute iron poisoning. Clinical experiences with 172 children. Clin Pediatr (Phila) 1966 Sep;5(9):531–535. doi: 10.1177/000992286600500907. [DOI] [PubMed] [Google Scholar]

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