Table 2.

Laboratory Parameters in Control and Cas IIgly-Treated Rats.

Parameter	Control (n = 8)	Tumor (n = 5)	Tumor + Cas IIgly, 0.4 mg/kg per day (n = 10)	Tumor + Cas IIgly, 0.8 mg/kg per day (n = 9)
Glucose (mg/dl)	147.96 ± 22.35	186.44 ± 61.08	116 ± 25.35*	111.22 ± 28.98*
BUN	24.40 ± 2.31	26.6 ± 5.24	25.4 ± 3.06	20.44 ± 2.92
Urea (mg/dl)	52.22 ± 4.93	56.92 ± 11.2	54.35 ± 6.55	43.74 ± 6.24
Creatinine (mg/dl)	0.63 ± 0.15	0.72 ± 0.044	0.63 ± 0.08	0.53 ± 0.07
Uric acid (mg/dl)	1.65 ± 0.43	4.16 ± 0.78†	2.43 ± 1.45	3.64 ± 0.77†
Bilirubin (mg/dl)	0.56 ± 0.20	1.1 ± 0.87	0.58 ± 0.21	0.53 ± 0.19
SGOT (U/l)	206.36 ± 102.56	344.22 ± 148.05	191.67 ± 73.02	211.44 ± 74.49
SGPT (U/l)	75.2 ± 17.2	67.12 ± 17.77	48.4 ± 13.7*	43.77 ± 10.73‡
Alkaline phosphatase (U/l)	431.22 ± 119.71	277.36 ± 61.81*	318.8 ± 153.46	238.22 ± 96.15*
GGT	1.25 ± 1.03	5.96 ± 4.11*	3.75 ± 2.96*	2.5 ± 1.37
Total protein (g/dl)	7.26 ± 0.17	6.84 ± 0.75	6.32 ± 0.84*	5.13 ± 1.0†
Albumin (g/dl)	1.57 ± 0.20	2.08 ± 1.18	1.4 ± 0.36	1.5 ± 1.25
Globulins (mg/dl)	5.66 ± 0.15	5.36 ± 0.55	ND	4.0 ± 0.58
A/G ratio	0.25 ± 0.03	0.278 ± 0.075	ND	0.27 ± 0.044

Results are expressed as mean ± SEM. Statistical significance was obtained by comparing untreated rats without tumor (Control) versus untreated rats with tumor or Cas IIgly-treated rats (0.4 and 0.8 mg/kg per day) with tumor.

^*P ≤ .05.

^†P ≤ .001.

^‡P ≤ .0001.