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. 2003 Jul;5(4):308–318. doi: 10.1016/S1476-5586(03)80024-6

Table 1.

Comparison of pO2 Data in Individual R3327 Dunning Prostate Rat Tumors.

Tumor Subline Size Number Baseline (21% O2) Oxygen Challenge (100% O2)
pO2 (Torr) Hypoxic Fractions (%) pO2 (Torr) Hypoxic Fractions (%)
Mean±SE Median HF5 HF10 Mean±SE Median HF5 HF10

H Small 6 33.8±4.4 30.1±4.4 9±2 16±2 137.2±22.9* 121.1±21.2* 1±1* 3±1*
Large 6 12.7±1.1 11.4±1.6 31±4 46±5 83.1±16.2* 68.5±20.0* 7±3* 10±4*
AT1 Small 7 10.4±2.1 7.9±2.3 42±7 61±7 62.4±13.1*, 55.4±21.0 19±7*, 24±9*,
Large 6 3.5±1.2, 2.1±1.0, 65±5, 83±3, 40.6±20.1 23.2±15.5 46±11 59±14

Small: <1.5 cm3; large: >3 cm3; HF5 or 10: hypoxic fraction (< 5 or 10 Torr).

*

P<.05 from baseline.

P<.05 from the small group.

P<.05 from the H tumors.