Abstract
The quality of the images produced by nuclear magnetic resonance (NMR) imaging has steadily improved over the past five years. Images of the head, thorax, and abdomen have clearly shown the normal anatomy. A clinical trial of NMR imaging has therefore been started in Aberdeen to assess its diagnostic accuracy and compare it with conventional radiography and other imaging technique. The first patient examined by whole-body NMR imaging had carcinoma of the oesophagus diagnosed on barium meal examination. A technetium-99m-sulphur colloid liver scan also showed hepatic metastases. NMR imaging showed a large tumour in the lower third of the oesophagus, and areas of increased proton spin-lattice relaxation time (T1) on a section through the liver corresponded with the metastases shown on the radionuclide scan. Increased areas of T1 were present in some vertebrae, and a technetium-99m bone scan confirmed the presence of bone metastases. The NMR images in this patient compared well with the images from other techniques. The continuing clinical trial may show that NMR is an accurate diagnostic aid which will complement existing techniques for diagnosing intrathoracic and intra-abdominal conditions.
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- Damadian R., Minkoff L., Goldsmith M. NMR in cancer: XXI. FONAR scan of the live human abdomen. Physiol Chem Phys. 1978;10(6):561–563. [PubMed] [Google Scholar]
- Edelstein W. A., Hutchison J. M., Johnson G., Redpath T. Spin warp NMR imaging and applications to human whole-body imaging. Phys Med Biol. 1980 Jul;25(4):751–756. doi: 10.1088/0031-9155/25/4/017. [DOI] [PubMed] [Google Scholar]
- Hinshaw W. S., Bottomley P. A., Holland G. N. Radiographic thin-section image of the human wrist by nuclear magnetic resonance. Nature. 1977 Dec 22;270(5639):722–723. doi: 10.1038/270722a0. [DOI] [PubMed] [Google Scholar]
- Holland G. N., Moore W. S., Hawkes R. C. NMR neuroradiography. Br J Radiol. 1980 Mar;53(627):253–255. doi: 10.1259/0007-1285-53-627-253. [DOI] [PubMed] [Google Scholar]
- Mansfield P., Maudsley A. A. Medical imaging by NMR. Br J Radiol. 1977 Mar;50(591):188–194. doi: 10.1259/0007-1285-50-591-188. [DOI] [PubMed] [Google Scholar]
- Mansfield P., Pykett I. L., Morris P. G. Human whole body line-scan imaging by NMR. Br J Radiol. 1978 Nov;51(611):921–922. doi: 10.1259/0007-1285-51-611-921. [DOI] [PubMed] [Google Scholar]
- Moore W. S., Holland G. N. Nuclear magnetic resonance imaging. Br Med Bull. 1980 Sep;36(3):297–299. doi: 10.1093/oxfordjournals.bmb.a071657. [DOI] [PubMed] [Google Scholar]






