Abstract
Two thousand three hundred and seventy strains of Shigella dysenteriae, Sh flexneri, and Sh boydii isolated in England and Wales from 1974 to 1978 were tested for resistance to 12 antimicrobial drugs. Eighty per cent of strains were resistant to one or more drugs, with sulphonamide resistance occurring most frequently. Resistance to streptomycin, tetracycline, ampicillin, and chloramphenicol increased during the period, as did the incidence of multiple resistance. Most infections due to Sh dysenteriae, Sh flexneri, and Sh boydii are acquired abroad, and the increasing incidence of drug resistance among these organisms contrasts with the decreasing incidence of resistance among the indigenous Sh sonnei. These findings may indicate the need for better control of antibiotic use, particularly in developing countries.
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Selected References
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- Davies J. R., Farrant W. N., Uttley A. H. Antibiotic resistance of Shigella sonnei. Lancet. 1970 Dec 5;2(7684):1157–1159. doi: 10.1016/s0140-6736(70)90341-7. [DOI] [PubMed] [Google Scholar]
- Gross R. J., Thomas L. V., Rowe B. Shigella dysenteriae, Sh flexneri, and Sh boydii infections in England and Wales: the importance of foreign travel. Br Med J. 1979 Sep 22;2(6192):744–744. [PMC free article] [PubMed] [Google Scholar]
- Haltalin K. C., Markley A. H., Woodman E. Agar plate dilution method for routine antibiotic susceptibility testing in a hospital laboratory. Am J Clin Pathol. 1973 Sep;60(3):384–394. doi: 10.1093/ajcp/60.3.384. [DOI] [PubMed] [Google Scholar]
- Rowe B., Gross R. J., Allen H. A. Shigella dysenteriae and Shigella boydii in England and Wales during 1972 and 1973. Br Med J. 1974 Dec 14;4(5945):641–642. doi: 10.1136/bmj.4.5945.641. [DOI] [PMC free article] [PubMed] [Google Scholar]