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American Journal of Public Health logoLink to American Journal of Public Health
. 1998 Jul;88(7):1025–1029. doi: 10.2105/ajph.88.7.1025

Lung cancer from passive smoking at work.

A J Wells
PMCID: PMC1508269  PMID: 9663148

Abstract

OBJECTIVES: This study was undertaken to determine whether exposure at work to environmental tobacco smoke is associated with an increased risk of lung cancer. METHODS: Data from 14 studies providing information on lung cancer and exposure to environmental tobacco smoke at work were examined. Six quality criteria were developed for determining usable data. A meta-analysis was performed to obtain a combined risk for those data that met the quality restrictions. RESULTS: Five studies met the quality standards. Their combined relative risk was 1.39 (95% confidence interval [CI] = 1.15, 1.68) based on 835 lung cancer cases. In various meta-analyses prepared by tobacco industry employees or consultants, no increase in risk was found. The main reason for this difference is that the earlier analysts failed to find errors in 2 underlying studies that resulted in overweighting of the odds ratios from those studies, both of which were less than unity. CONCLUSIONS: When appropriate cognizance is taken of the quality of data inputs, the increase in lung cancer risk from workplace exposure to environmental tobacco smoke is about the same as that from household exposure.

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Selected References

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  1. Biggerstaff B. J., Tweedie R. L., Mengersen K. L. Passive smoking in the workplace: classical and Bayesian meta-analyses. Int Arch Occup Environ Health. 1994;66(4):269–277. doi: 10.1007/BF00454366. [DOI] [PubMed] [Google Scholar]
  2. Brownson R. C., Alavanja M. C., Hock E. T., Loy T. S. Passive smoking and lung cancer in nonsmoking women. Am J Public Health. 1992 Nov;82(11):1525–1530. doi: 10.2105/ajph.82.11.1525. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Chappell W. R., Gratt L. B. A graphical method for pooling epidemiological studies. Am J Public Health. 1996 May;86(5):748–750. doi: 10.2105/ajph.86.5.748. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Fontham E. T., Correa P., Reynolds P., Wu-Williams A., Buffler P. A., Greenberg R. S., Chen V. W., Alterman T., Boyd P., Austin D. F. Environmental tobacco smoke and lung cancer in nonsmoking women. A multicenter study. JAMA. 1994 Jun 8;271(22):1752–1759. [PubMed] [Google Scholar]
  5. Fontham E. T., Correa P., WuWilliams A., Reynolds P., Greenberg R. S., Buffler P. A., Chen V. W., Boyd P., Alterman T., Austin D. F. Lung cancer in nonsmoking women: a multicenter case-control study. Cancer Epidemiol Biomarkers Prev. 1991 Nov-Dec;1(1):35–43. [PubMed] [Google Scholar]
  6. Garfinkel L., Auerbach O., Joubert L. Involuntary smoking and lung cancer: a case-control study. J Natl Cancer Inst. 1985 Sep;75(3):463–469. [PubMed] [Google Scholar]
  7. Janerich D. T., Thompson W. D., Varela L. R., Greenwald P., Chorost S., Tucci C., Zaman M. B., Melamed M. R., Kiely M., McKneally M. F. Lung cancer and exposure to tobacco smoke in the household. N Engl J Med. 1990 Sep 6;323(10):632–636. doi: 10.1056/NEJM199009063231003. [DOI] [PubMed] [Google Scholar]
  8. Kabat G. C., Stellman S. D., Wynder E. L. Relation between exposure to environmental tobacco smoke and lung cancer in lifetime nonsmokers. Am J Epidemiol. 1995 Jul 15;142(2):141–148. doi: 10.1093/oxfordjournals.aje.a117612. [DOI] [PubMed] [Google Scholar]
  9. Kabat G. C., Wynder E. L. Lung cancer in nonsmokers. Cancer. 1984 Mar 1;53(5):1214–1221. doi: 10.1002/1097-0142(19840301)53:5<1214::aid-cncr2820530532>3.0.co;2-8. [DOI] [PubMed] [Google Scholar]
  10. Kalandidi A., Katsouyanni K., Voropoulou N., Bastas G., Saracci R., Trichopoulos D. Passive smoking and diet in the etiology of lung cancer among non-smokers. Cancer Causes Control. 1990 Jul;1(1):15–21. doi: 10.1007/BF00053179. [DOI] [PubMed] [Google Scholar]
  11. LeVois M. E., Layard M. W. Inconsistency between workplace and spousal studies of environmental tobacco smoke and lung cancer. Regul Toxicol Pharmacol. 1994 Jun;19(3):309–316. doi: 10.1006/rtph.1994.1026. [DOI] [PubMed] [Google Scholar]
  12. Lee P. N., Chamberlain J., Alderson M. R. Relationship of passive smoking to risk of lung cancer and other smoking-associated diseases. Br J Cancer. 1986 Jul;54(1):97–105. doi: 10.1038/bjc.1986.157. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Muscat J. E., Wynder E. L. Exposure to environmental tobacco smoke and the risk of heart attack. Int J Epidemiol. 1995 Aug;24(4):715–719. doi: 10.1093/ije/24.4.715. [DOI] [PubMed] [Google Scholar]
  14. Reynolds P., von Behren J., Fontham E. T., Correa P., Wu A., Buffler P. A., Greenberg R. S. Occupational exposure to environmental tobacco smoke. JAMA. 1996 Feb 14;275(6):441–442. doi: 10.1001/jama.1996.03530300025019. [DOI] [PubMed] [Google Scholar]
  15. Schwartz A. G., Yang P., Swanson G. M. Familial risk of lung cancer among nonsmokers and their relatives. Am J Epidemiol. 1996 Sep 15;144(6):554–562. doi: 10.1093/oxfordjournals.aje.a008965. [DOI] [PubMed] [Google Scholar]
  16. Shimizu H., Morishita M., Mizuno K., Masuda T., Ogura Y., Santo M., Nishimura M., Kunishima K., Karasawa K., Nishiwaki K. A case-control study of lung cancer in nonsmoking women. Tohoku J Exp Med. 1988 Apr;154(4):389–397. doi: 10.1620/tjem.154.389. [DOI] [PubMed] [Google Scholar]
  17. Wells A. J., Henley S. J. Involuntary smoking and lung cancer: a case-control study. J Natl Cancer Inst. 1997 Jun 4;89(11):821–822. doi: 10.1093/jnci/89.11.821. [DOI] [PubMed] [Google Scholar]
  18. Wu-Williams A. H., Dai X. D., Blot W., Xu Z. Y., Sun X. W., Xiao H. P., Stone B. J., Yu S. F., Feng Y. P., Ershow A. G. Lung cancer among women in north-east China. Br J Cancer. 1990 Dec;62(6):982–987. doi: 10.1038/bjc.1990.421. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Wu A. H., Henderson B. E., Pike M. C., Yu M. C. Smoking and other risk factors for lung cancer in women. J Natl Cancer Inst. 1985 Apr;74(4):747–751. [PubMed] [Google Scholar]

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