Abstract
OBJECTIVES: Three filters were tested for in situ efficacy in reducing bacterial contamination associated with injection drug use. METHODS: In a self-matched control design with blinded laboratory testing, injection drug users were asked to use 3 filters in random succession when loading their syringes with drug solute. RESULTS: The 0.22-micron filter proved significantly better than both the cigarette filter (relative risk [RR] = 18.0) and the 20-micron filter (RR = 4.5) in rendering syringes bacteria-free. CONCLUSIONS: The 15- to 20-micron syringe filter currently provided injection drug users in Switzerland does not significantly reduce contamination associated with common bacterial infections among users. Filters with pore width 1/100th as large are recommended.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bergstein J. M., Baker E. J., 4th, Aprahamian C., Schein M., Wittmann D. H. Soft tissue abscesses associated with parenteral drug abuse: presentation, microbiology, and treatment. Am Surg. 1995 Dec;61(12):1105–1108. [PubMed] [Google Scholar]
- Henriksen B. M., Albrektsen S. B., Simper L. B., Gutschik E. Soft tissue infections from drug abuse. A clinical and microbiological review of 145 cases. Acta Orthop Scand. 1994 Dec;65(6):625–628. doi: 10.3109/17453679408994618. [DOI] [PubMed] [Google Scholar]
- Moustoukas N. M., Nichols R. L., Smith J. W., Garey R. E., Egan R. R. Contaminated street heroin. Relationship to clinical infections. Arch Surg. 1983 Jun;118(6):746–749. doi: 10.1001/archsurg.1983.01390060064014. [DOI] [PubMed] [Google Scholar]
- Orangio G. R., Pitlick S. D., Della Latta P., Mandel L. J., Marino C., Guarneri J. J., Giron J. A., Margolis I. B. Soft tissue infections in parenteral drug abusers. Ann Surg. 1984 Jan;199(1):97–100. doi: 10.1097/00000658-198401000-00016. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tuazon C. U., Hill R., Sheagren J. N. Microbiologic study of street heroin and injection paraphernalia. J Infect Dis. 1974 Mar;129(3):327–329. doi: 10.1093/infdis/129.3.327. [DOI] [PubMed] [Google Scholar]
