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. 1999 May;89(5):762–764. doi: 10.2105/ajph.89.5.762

The Resource Mothers Program for Maternal Phenylketonuria.

P S St James 1, E Shapiro 1, S E Waisbren 1
PMCID: PMC1508738  PMID: 10224992

Abstract

OBJECTIVES: The purpose of this study was to measure the effectiveness of resource mothers in reducing adverse consequences of maternal phenylketonuria. METHODS: Nineteen pregnancies in the resource mothers group were compared with 64 pregnancies in phenylketonuric women without resource mothers. Weeks to metabolic control and offspring outcome were measured. RESULTS: Mean number of weeks to metabolic control was 8.5 (SE = 2.2) in the resource mothers group, as compared with 16.1 (SE = 1.7) in the comparison group. Infants of women in the resource mothers group had larger birth head circumferences and higher developmental quotients. CONCLUSIONS: The resource mothers program described here improves metabolic control in pregnant women with phenylketonuria.

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Selected References

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