Abstract
Experiments on albino rats showed that short-term overdosage with dihydrotachysterol, in amounts causing only traces of soft-tissue calcification, induced a very pronounced calcium deposition in the heart, aorta, and kidney when the animals were simultaneously treated with phenylbutazone. Special attention is called to the fact that, under these experimental conditions, it is possible to obtain consistently a massive calcium deposition in the stroma of the renal papilla similar to that seen in “Randall's plaques” during the development of urolithiasis in man.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Randall A. THE ORIGIN AND GROWTH OF RENAL CALCULI. Ann Surg. 1937 Jun;105(6):1009–1027. doi: 10.1097/00000658-193706000-00014. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SELYE H. Rolle der Nebennierenrinde bei der Entstehung verschiedenartiger Blutgefässveränderungen. Munch Med Wochenschr. 1956 Aug 3;98(31):1015–1018. [PubMed] [Google Scholar]