Abstract
Carrier strontium had relatively little effect on the retention of an oral dose of radioactive strontium by the rat when it was administered immediately after the radioactive dose. The proportion of the radioactive dose which was excreted in the urine, on the other hand, increased progressively with the carrier dose. There was a decreased uptake of radioactive strontium in rats fed on a special low strontium diet. The effects of dietary strontium are discussed. Evidence was found of a discrimination by the rat against strontium in favour of calcium which was accounted for, at least in part, by a preferential urinary excretion of strontium.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ALEXANDER G. V., NUSBAUM R. E., MACDONALD N. S. The relative retention of strontium and calcium in bone tissue. J Biol Chem. 1956 Feb;218(2):911–919. [PubMed] [Google Scholar]
- COID C. R., JONES H. G. The passage of strontium across the intestinal wall of the rat. Clin Sci. 1956 Nov;15(4):541–549. [PubMed] [Google Scholar]
- COMAR C. L., NOLD M. M., WASSERMAN R. H. Strontium-calcium discrimination factors in the rat. Proc Soc Exp Biol Med. 1956 Aug-Sep;92(4):859–863. doi: 10.3181/00379727-92-22636. [DOI] [PubMed] [Google Scholar]
- HANSARD S. L., COMAR C. L., PLUMLEE M. P. Effect of calcium status, mass of calcium administered and age on Ca 45 metabolism in the rat. Proc Soc Exp Biol Med. 1951 Nov;78(2):455–460. doi: 10.3181/00379727-78-19102. [DOI] [PubMed] [Google Scholar]
- KIDMAN B., TUTT M., VAUGHAN J. The retention and excretion of radioactive strontium and yttrium (Sr89, Sr90 and Y 90) in the healthy rabbit. J Pathol Bacteriol. 1950 Apr;62(2):209–227. doi: 10.1002/path.1700620208. [DOI] [PubMed] [Google Scholar]
- MacDONALD N. S., NUSBAUM R. E., EZMIRLIAN F., BARBERA R. C., ALEXANDER G. V., SPAIN P., ROUNDS D. E. Gastrointestinal absorption of ions. I. Agents diminishing absorption of strontium. J Pharmacol Exp Ther. 1952 Mar;104(3):348–353. [PubMed] [Google Scholar]
- Martland M., Robison R. Possible Significance of Hexosephosphoric Esters in Ossification: Part VI. Phosphoric Esters in Blood-Plasma. Biochem J. 1926;20(4):847–855. doi: 10.1042/bj0200847. [DOI] [PMC free article] [PubMed] [Google Scholar]