Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1995 Mar;72(3):233–234. doi: 10.1136/adc.72.3.233

Spot urine pancreolauryl test for use in infancy.

M R Green 1, S Austin 1, P McClean 1, S Jolliffe 1, L T Weaver 1
PMCID: PMC1511069  PMID: 7741571

Abstract

As a simple non-invasive test of possible pancreatic insufficiency 10 healthy infants, 13 infants with cystic fibrosis, and nine infants with unexplained diarrhoea and failure to thrive were given an emulsion containing fluorescein dilaurate and mannitol by mouth. A spot urine specimen was collected and results expressed as urinary fluorescein to mannitol ratios. Sensitivity of the test was 96% and specificity was 95%.

Full text

PDF
233

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Green M. R., Austin S., Weaver L. T. Dual marker one day pancreolauryl test. Arch Dis Child. 1993 May;68(5):649–652. doi: 10.1136/adc.68.5.649. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Laker M. F., Bull H. J., Menzies I. S. Evaluation of mannitol for use as a probe marker of gastrointestinal permeability in man. Eur J Clin Invest. 1982 Dec;12(6):485–491. doi: 10.1111/j.1365-2362.1982.tb02230.x. [DOI] [PubMed] [Google Scholar]
  3. Lunn P. G., Northrop C. A., Northrop A. J. Automated enzymatic assays for the determination of intestinal permeability probes in urine. 2. Mannitol. Clin Chim Acta. 1989 Aug 15;183(2):163–170. doi: 10.1016/0009-8981(89)90332-x. [DOI] [PubMed] [Google Scholar]
  4. Meyer-Bertenrath J. G. Lipolytic enzymes of the human pancreas. I. A highly sensitive, specific, and simple measurement of cholesterol ester hydrolase activity. Enzyme. 1982;28(4):336–342. [PubMed] [Google Scholar]
  5. Roberts S. B., Lucas A. Measurement of urinary constituents and output using disposable napkins. Arch Dis Child. 1985 Nov;60(11):1021–1024. doi: 10.1136/adc.60.11.1021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Weaver L. T., Chapman P. D., Madeley C. R., Laker M. F., Nelson R. Intestinal permeability changes and excretion of micro-organisms in stools of infants with diarrhoea and vomiting. Arch Dis Child. 1985 Apr;60(4):326–332. doi: 10.1136/adc.60.4.326. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES