Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1996 Apr;74(4):350–351. doi: 10.1136/adc.74.4.350

Hypocitraturia in patients with urolithiasis.

T Akçay 1, D Konukoğlu 1, C Celik 1
PMCID: PMC1511487  PMID: 8669940

Abstract

The urinary citrate/creatinine ratio was evaluated in 25 children with idiopathic calcium urolithiasis and 24 controls. The mean (SD) urinary citrate/creatinine ratio in controls and patients was 0.510 (0.205) and 0.181 (0.076), respectively, a statistically significant difference. In neither group was there a relation between age and urinary citrate excretion.

Full text

PDF
350

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baggio B., Gambaro G., Favaro S., Borsatti A., Pavanello L., Siviero B., Zacchello G., Rizzoni G. F. Juvenile renal stone disease: a study of urinary promoting and inhibiting factors. J Urol. 1983 Dec;130(6):1133–1135. doi: 10.1016/s0022-5347(17)51721-8. [DOI] [PubMed] [Google Scholar]
  2. Elliot J. S., Ribeiro M. E. The urinary excretion of citric, hippuric, and lactic acid in normal adults and in patients with calcium oxalate urinary calculus disease. Invest Urol. 1972 Jul;10(1):102–106. [PubMed] [Google Scholar]
  3. Fleisch H. Inhibitors and promoters of stone formation. Kidney Int. 1978 May;13(5):361–371. doi: 10.1038/ki.1978.54. [DOI] [PubMed] [Google Scholar]
  4. Hosking D. H., Wilson J. W., Liedtke R. R., Smith L. H., Wilson D. M. Urinary citrate excretion in normal persons and patients with idiopathic calcium urolithiasis. J Lab Clin Med. 1985 Dec;106(6):682–689. [PubMed] [Google Scholar]
  5. Lama G., Carbone M. G., Marrone N., Russo P., Spagnuolo G. Promoters and inhibitors of calcium urolithiasis in children. Child Nephrol Urol. 1990;10(2):81–84. [PubMed] [Google Scholar]
  6. Lonsdale K. Human stones. Science. 1968 Mar 15;159(3820):1199–1207. doi: 10.1126/science.159.3820.1199. [DOI] [PubMed] [Google Scholar]
  7. Menon M., Mahle C. J. Urinary citrate excretion in patients with renal calculi. J Urol. 1983 Jun;129(6):1158–1160. doi: 10.1016/s0022-5347(17)52618-x. [DOI] [PubMed] [Google Scholar]
  8. Meyer J. L., Smith L. H. Growth of calcium oxalate crystals. II. Inhibition by natural urinary crystal growth inhibitors. Invest Urol. 1975 Jul;13(1):36–39. [PubMed] [Google Scholar]
  9. Miller L. A., Stapleton F. B. Urinary citrate excretion in children with hypercalciuria. J Pediatr. 1985 Aug;107(2):263–266. doi: 10.1016/s0022-3476(85)80144-x. [DOI] [PubMed] [Google Scholar]
  10. Nicar M. J., Skurla C., Sakhaee K., Pak C. Y. Low urinary citrate excretion in nephrolithiasis. Urology. 1983 Jan;21(1):8–14. doi: 10.1016/0090-4295(83)90113-9. [DOI] [PubMed] [Google Scholar]
  11. Nikkilä M., Koivula T., Jokela H. Urinary citrate excretion in patients with urolithiasis and normal subjects. Eur Urol. 1989;16(5):382–385. doi: 10.1159/000471622. [DOI] [PubMed] [Google Scholar]
  12. Norman M. E., Feldman N. I., Cohn R. M., Roth K. S., McCurdy D. K. Urinary citrate excretion in the diagnosis of distal renal tubular acidosis. J Pediatr. 1978 Mar;92(3):394–400. doi: 10.1016/s0022-3476(78)80426-0. [DOI] [PubMed] [Google Scholar]
  13. Norman M. E., Feldman N. I., Cohn R. M., Roth K. S., McCurdy D. K. Urinary citrate excretion in the diagnosis of distal renal tubular acidosis. J Pediatr. 1978 Mar;92(3):394–400. doi: 10.1016/s0022-3476(78)80426-0. [DOI] [PubMed] [Google Scholar]
  14. Rudman D., Kutner M. H., Redd S. C., 2nd, Waters W. C., 4th, Gerron G. G., Bleier J. Hypocitraturia in calcium nephrolithiasis. J Clin Endocrinol Metab. 1982 Dec;55(6):1052–1057. doi: 10.1210/jcem-55-6-1052. [DOI] [PubMed] [Google Scholar]
  15. Schwille P. O., Scholz D., Paulus M., Engelhardt W., Sigel A. Citrate in daily and fasting urine: results of controls, patients with recurrent idiopathic calcium urolithiasis, and primary hyperparathyroidism. Invest Urol. 1979 May;16(6):457–462. [PubMed] [Google Scholar]
  16. Welshman S. G., McGeown M. G. Urinary citrate excretion in stone-formers and normal controls. Br J Urol. 1976 Feb;48(1):7–11. doi: 10.1111/j.1464-410x.1976.tb02731.x. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES