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. 1996 Nov;75(5):440–443. doi: 10.1136/adc.75.5.440

Delayed gastric emptying: a novel gastrointestinal finding in Turner's syndrome.

A Staiano 1, M Salerno 1, S Di Maio 1, G Marsullo 1, A Marino 1, D Concolino 1, P Strisciuglio 1
PMCID: PMC1511766  PMID: 8957960

Abstract

AIM: To evaluate gastric emptying in girls with Turner's syndrome to detect if gastrointestinal motor dysfunction was present. SUBJECTS: Thirteen girls (mean age 8.1 years) with Turner's syndrome, seven girls with familial short stature (6.1 years), and eight control girls (7.6 years). METHODS: Gastric emptying studies were performed by using 500 microCi of technetium 99m-sulphur colloid bound to a scrambled egg, and scintigraphic measurements were made for 60 to 90 minutes. RESULTS: Mean (SD) percentage retention of gastric isotope was significantly greater in girls with Turner's syndrome than in children with short stature and in controls. Furthermore, in contrast with control subjects, in whom there was an inverse linear relationship between gastric emptying rate and body mass index, in children with Turner's syndrome the delay in gastric emptying was independent of the body mass. CONCLUSIONS: The results of the study suggest that delayed gastric emptying is detectable in girls with Turner's syndrome independent of age, body mass index, karyotype, and growth promoting treatment.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brook C. G. Turner syndrome. Arch Dis Child. 1986 Mar;61(3):305–309. doi: 10.1136/adc.61.3.305. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Chen H., Faigenbaum D., Weiss H. Psychosocial aspects of patients with the Ullrich-Turner syndrome. Am J Med Genet. 1981;8(2):191–203. doi: 10.1002/ajmg.1320080210. [DOI] [PubMed] [Google Scholar]
  3. Hall J. G., Gilchrist D. M. Turner syndrome and its variants. Pediatr Clin North Am. 1990 Dec;37(6):1421–1440. doi: 10.1016/s0031-3955(16)37018-3. [DOI] [PubMed] [Google Scholar]
  4. Horowitz M., Collins P. J., Cook D. J., Harding P. E., Shearman D. J. Abnormalities of gastric emptying in obese patients. Int J Obes. 1983;7(5):415–421. [PubMed] [Google Scholar]
  5. Horowitz M., Maddox A., Maddern G. J., Wishart J., Collins P. J., Shearman D. J. Gastric and esophageal emptying in dystrophia myotonica. Effect of metoclopramide. Gastroenterology. 1987 Mar;92(3):570–577. doi: 10.1016/0016-5085(87)90003-5. [DOI] [PubMed] [Google Scholar]
  6. Lavigne M. E., Wiley Z. D., Meyer J. H., Martin P., MacGregor I. L. Gastric emptying rates of solid food in relation to body size. Gastroenterology. 1978 Jun;74(6):1258–1260. [PubMed] [Google Scholar]
  7. Lavigne M. E., Wiley Z. D., Meyer J. H., Martin P., MacGregor I. L. Gastric emptying rates of solid food in relation to body size. Gastroenterology. 1978 Jun;74(6):1258–1260. [PubMed] [Google Scholar]
  8. Marshall W. A., Tanner J. M. Variations in pattern of pubertal changes in girls. Arch Dis Child. 1969 Jun;44(235):291–303. doi: 10.1136/adc.44.235.291. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Mathisen B., Reilly S., Skuse D. Oral-motor dysfunction and feeding disorders of infants with Turner syndrome. Dev Med Child Neurol. 1992 Feb;34(2):141–149. doi: 10.1111/j.1469-8749.1992.tb14980.x. [DOI] [PubMed] [Google Scholar]
  10. Ogata T., Matsuo N. Turner syndrome and female sex chromosome aberrations: deduction of the principal factors involved in the development of clinical features. Hum Genet. 1995 Jun;95(6):607–629. doi: 10.1007/BF00209476. [DOI] [PubMed] [Google Scholar]
  11. Palmer C. G., Reichmann A. Chromosomal and clinical findings in 110 females with Turner syndrome. Hum Genet. 1976 Dec 29;35(1):35–49. doi: 10.1007/BF00295617. [DOI] [PubMed] [Google Scholar]
  12. Price W. H. A high incidence of chronic inflammatory bowel disease in patients with Turner's syndrome. J Med Genet. 1979 Aug;16(4):263–266. doi: 10.1136/jmg.16.4.263. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Sasaki H., Nagulesparan M., Dubois A., Samloff I. M., Straus E., Sievers M. L., Unger R. H. Gastric function and obesity: gastric emptying, gastric acid secretion, and plasma pepsinogen. Int J Obes. 1984;8(2):183–190. [PubMed] [Google Scholar]
  14. Staiano A., Corazziari E., Andreotti M. R., Clouse R. E. Esophageal motility in children with Hirschsprung's disease. Am J Dis Child. 1991 Mar;145(3):310–313. doi: 10.1001/archpedi.1991.02160030078026. [DOI] [PubMed] [Google Scholar]
  15. Staiano A., Cucchiara S., Del Giudice E., Andreotti M. R., Minella R. Disorders of oesophageal motility in children with psychomotor retardation and gastro-oesophageal reflux. Eur J Pediatr. 1991 Jul;150(9):638–641. doi: 10.1007/BF02072624. [DOI] [PubMed] [Google Scholar]
  16. Staiano A., Del Giudice E., Romano A., Andreotti M. R., Santoro L., Marsullo G., Rippa P. G., Iovine A., Salvatore M. Upper gastrointestinal tract motility in children with progressive muscular dystrophy. J Pediatr. 1992 Nov;121(5 Pt 1):720–724. doi: 10.1016/s0022-3476(05)81899-2. [DOI] [PubMed] [Google Scholar]

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