Abstract
A review of heart replacement involves discussion of the artificial heart and the cardiac homograft. The mechanical substitute shows destruction of blood cellular elements and clot formation, regardless of the type of pump used. Significant postoperative survival remains as the major goal. Animals having homograft substitutions show prolonged survival and good cardiac function. Philosophical and legal problems rank above the rejection phenomenon in curtailing clinical isotopic replacement.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- AKUTSU T., MIRKOVITCH V., TOPAZ S. R., KOLFF W. J. Silastic sac type of artifical heart and its use in calves. Trans Am Soc Artif Intern Organs. 1963;9:281–285. [PubMed] [Google Scholar]
- BERNSTEIN E. F., CASTANEDA A. R., VARCO R. L. SOME BIOLOGIC LIMITATIONS TO PROLONGED BLOOD PUMPING. Trans Am Soc Artif Intern Organs. 1965;11:118–121. doi: 10.1097/00002480-196504000-00023. [DOI] [PubMed] [Google Scholar]
- BLACKSHEAR P. L., Jr, DORMAN F. D., STEINBACH J. H. SOME MECHANICAL EFFECTS THAT INFLUENCE HEMOLYSIS. Trans Am Soc Artif Intern Organs. 1965;11:112–117. doi: 10.1097/00002480-196504000-00022. [DOI] [PubMed] [Google Scholar]
- Dong E., Jr, Lower R. R., Hurley E. J., Shumway N. E. Transplantation of the heart. Dis Chest. 1965 Nov;48(5):455–457. doi: 10.1378/chest.48.5.455. [DOI] [PubMed] [Google Scholar]
- GRAEDEL F., AKUTSU T., CHAPTAL P. A., KANTROWITZ A. SUCCESSFUL HEMODYNAMIC RESULTS WITH A NEW, U-SHAPED AUXILIARY VENTRICLE. Trans Am Soc Artif Intern Organs. 1965;11:277–283. doi: 10.1097/00002480-196504000-00052. [DOI] [PubMed] [Google Scholar]
- HALL C. W., AKERS W. W., O'BANNON W., LIOTTA D., DEBAKEY M. E. INTRAVENTRICULAR ARTIFICIAL HEART. Trans Am Soc Artif Intern Organs. 1965;11:263–264. doi: 10.1097/00002480-196504000-00049. [DOI] [PubMed] [Google Scholar]
- HURLEY E. J., DONG E., Jr, STOFER R. C., SHUMWAY N. E. Isotopic replacement of the totally excised canine heart. J Surg Res. 1962 Mar;2:90–94. doi: 10.1016/s0022-4804(62)80002-x. [DOI] [PubMed] [Google Scholar]
- Hurley E. J., Lower R. R., Shumway N. E. Stokes-Adams attacks in transplanted hearts. Surg Forum. 1965;16:218–219. [PubMed] [Google Scholar]
- KUSSEROW B. K., MACHANIC B., COLLINS F. M., Jr, CLAPP J. F., 3rd CHANGES OBSERVED IN BLOOD CORPUSCLES AFTER PROLONGED PERFUSIONS WITH TWO TYPES OF BLOOD PUMPS. Trans Am Soc Artif Intern Organs. 1965;11:122–126. doi: 10.1097/00002480-196504000-00024. [DOI] [PubMed] [Google Scholar]
- LIOTTA D., MANESS J., BOURLAND H., RODWELL D., HALL C. W., DEBAKEY M. E. RECENT MODIFICATIONS IN THE IMPLANTABLE LEFT VENTRICULAR BYPASS. Trans Am Soc Artif Intern Organs. 1965;11:284–290. doi: 10.1097/00002480-196504000-00053. [DOI] [PubMed] [Google Scholar]
- LOWER R. R., DONG E., Jr, SHUMWAY N. E. LONG-TERM SURVIVAL OF CARDIAC HOMOGRAFTS. Surgery. 1965 Jul;58:110–119. [PubMed] [Google Scholar]
- LOWER R. R., SHUMWAY N. E. Studies on orthotopic homotransplantation of the canine heart. Surg Forum. 1960;11:18–19. [PubMed] [Google Scholar]
- LOWER R. R., STOFER R. C., HURLEY E. J., DONG E., Jr, COHN R. B., SHUMWAY N. E. Successful homotransplantation of the canine heart after anoxic preservation for seven hours. Am J Surg. 1962 Aug;104:302–306. doi: 10.1016/0002-9610(62)90332-x. [DOI] [PubMed] [Google Scholar]
- NOSE Y., TOPAZ S., SENGUPTA A., TRETBAR L. L., KOLIFF W. J. ARTIFICIAL HEARTS INSIDE THE PERICARDIAL SAC IN CALVES. Trans Am Soc Artif Intern Organs. 1965;11:255–262. doi: 10.1097/00002480-196504000-00048. [DOI] [PubMed] [Google Scholar]
- PIERCE W. S., MORRIS L., GARDINER B. N., BURNEY R. G., LEPPIK I., MALMUD L., DANIELSON G. K. EXPERIMENTAL USE OF A SINGLE MECHANICAL VENTRICLE TO REPLACE THE DOG'S HEART. Trans Am Soc Artif Intern Organs. 1965;11:271–276. doi: 10.1097/00002480-196504000-00051. [DOI] [PubMed] [Google Scholar]
- PIERSON R. M., CAMP G. B., MATHIS M. V. ROLLER PUMP FOR ARTIFICIAL HEARTS USING MULTI-CHAMBERED RUBBER TUBING. Trans Am Soc Artif Intern Organs. 1965;11:68–75. doi: 10.1097/00002480-196504000-00014. [DOI] [PubMed] [Google Scholar]
- REEMTSMA K., WILLIAMSON W. E., Jr, IGLESIAS F., PENA E., SAYEGH S. F., CREECH O., Jr Studies in homologous canine heart transplantation:prolongation of survival with a folic acid antagonist. Surgery. 1962 Jul;52:127–133. [PubMed] [Google Scholar]
- SHUMWAY N. E., LOWER R. R. SPECIAL PROBLEMS IN TRANSPLANTATION OF THE HEART. Ann N Y Acad Sci. 1964 Nov 30;120:773–777. doi: 10.1111/j.1749-6632.1964.tb34768.x. [DOI] [PubMed] [Google Scholar]
