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. 1972 Aug;117(2):25–39.

Acute Pancreatitis

Michael C Geokas
PMCID: PMC1518611  PMID: 4559467

Abstract

For many decades two types of acute pancreatitis have been recognized: the edematous or interstitial and the hemorrhagic or necrotic. In most cases acute pancreatitis is associated with alcoholism or biliary tract disease. Elevated serum or urinary α-amylase is the most important finding in diagnosis. The presence of methemalbumin in serum and in peritoneal or pleural fluid supports the diagnosis of the hemorrhagic form of the disease in patients with a history and enzyme studies suggestive of pancreatitis.

There is no characteristic clinical picture in acute pancreatitis, and its complications are legion. Pancreatic pseudocyst is probably the most common and pancreatic abscess is the most serious complication.

The pathogenetic principle is autodigestion, but the precise sequence of biochemical events is unclear, especially the mode of trypsinogen activation and the role of lysosomal hydrolases. A host of metabolic derangements have been identified in acute pancreatitis, involving lipid, glucose, calcium and magnesium metabolism and changes of the blood clotting mechanism, to name but a few.

Medical treatment includes intestinal decompression, analgesics, correction of hypovolemia and other supportive and protective measures. Surgical exploration is advisable in selected cases, when the diagnosis is in doubt, and is considered imperative in the presence of certain complications, especially pancreatic abscess.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adams J. T., Libertino J. A., Schwartz S. I. Significance of an elevated serum amylase. Surgery. 1968 Jun;63(6):877–884. [PubMed] [Google Scholar]
  2. Ambromovage A. M., Howard J. M., Pairent F. W. The twenty-four hour excretion of amylase and lipase in the urine: correlation with the functional state and operative injury of the pancreas. Ann Surg. 1968 Apr;167(4):539–546. doi: 10.1097/00000658-196804000-00010. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Ances I. G., McClain C. A. Acute pancreatitis following the use of thiazide in pregnancy. South Med J. 1971 Mar;64(3):267–269. doi: 10.1097/00007611-197103000-00003. [DOI] [PubMed] [Google Scholar]
  4. Anderson M. C., Schiller W. R. Microcirculatory dynamics in the normal and inflamed pancreas. Am J Surg. 1968 Jan;115(1):118–127. doi: 10.1016/0002-9610(68)90139-6. [DOI] [PubMed] [Google Scholar]
  5. Anderson M. C., Toronto I. R., Needleman S. B., Gramatica L. Assessment of methemalbumin as a diagnostic test for acute pancreatitis. Arch Surg. 1969 Jun;98(6):776–780. doi: 10.1001/archsurg.1969.01340120124023. [DOI] [PubMed] [Google Scholar]
  6. Andersson G., Johnson S. R. Treatment of acute necrotizing pancreatitis. Acta Chir Scand. 1968;134(3):311–313. [PubMed] [Google Scholar]
  7. Attard J. Pseudocyst of the pancreas in a child. Br J Surg. 1969 Mar;56(3):235–238. doi: 10.1002/bjs.1800560321. [DOI] [PubMed] [Google Scholar]
  8. Avioli L. V., Birge S. J., Scott S., Shieber W. Role of the thyroid gland during glucagon-induced hypocalcemia in the dog. Am J Physiol. 1969 Apr;216(4):939–945. doi: 10.1152/ajplegacy.1969.216.4.939. [DOI] [PubMed] [Google Scholar]
  9. Babson A. L., Tenney S. A., Megraw R. E. New amylase substrate and assay procedure. Clin Chem. 1970 Jan;16(1):39–43. [PubMed] [Google Scholar]
  10. Baden H., Jordal K., Lund F., Zachariae F. Prophylactic and curative action of Trasylol in pancreatitis. A double-blind trial. Scand J Gastroenterol. 1969;4(3):291–295. [PubMed] [Google Scholar]
  11. Bagdade J. D. Diabetic lipaemia complicating acute pancreatitis. Lancet. 1969 Nov 15;2(7629):1041–1043. doi: 10.1016/s0140-6736(69)90645-x. [DOI] [PubMed] [Google Scholar]
  12. Balfour J. F. Pancreatic pseudocysts: complications and their relation to the timing of treatment. Surg Clin North Am. 1970 Apr;50(2):395–402. doi: 10.1016/s0039-6109(16)39087-9. [DOI] [PubMed] [Google Scholar]
  13. Bardenheier J. A., 3rd, Quintero O., Barner H. B. False aneurysm in a pancreatic pseudocyst. Ann Surg. 1970 Jul;172(1):53–55. [PMC free article] [PubMed] [Google Scholar]
  14. Bardenheier J. A., Kaminski D. L., Willman V. L. Pancreatitis after biliary tract surgery. Am J Surg. 1968 Nov;116(5):773–776. doi: 10.1016/0002-9610(68)90366-8. [DOI] [PubMed] [Google Scholar]
  15. Bartholomew C. Acute scorpion pancreatitis in Trinidad. Br Med J. 1970 Mar 14;1(5697):666–668. doi: 10.1136/bmj.1.5697.666. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Bellet S., Yoshimine N., DeCastro O. A., Roman L., Parmar S. S., Sandberg H. Effects of alcohol ingestion on growth hormone levels: their relation to 11-hydroxycorticoid levels and serum FFA. Metabolism. 1971 Aug;20(8):762–769. doi: 10.1016/s0026-0495(71)80006-9. [DOI] [PubMed] [Google Scholar]
  17. Berk J. E., Smith B. H., Akrawi M. M. Pregnancy pancreatitis. Am J Gastroenterol. 1971 Sep;56(3):216–226. [PubMed] [Google Scholar]
  18. Berndt W., Müller-Wieland K. The role of lysosomal proteases in the pathogenesis of pancreatitis. Pol Arch Med Wewn. 1970 Apr-May;4(4):535–537. [PubMed] [Google Scholar]
  19. Berne T. V., Edmondson H. A. Colonic fistulization due to pancreatitis. Am J Surg. 1966 Mar;111(3):359–363. doi: 10.1016/s0002-9610(66)80012-0. [DOI] [PubMed] [Google Scholar]
  20. Bieth J., Metais P. The simultaneous presence of trypsin and trypsin inhibitors in some pathological effusions. Clin Chim Acta. 1968 Dec;22(4):639–642. doi: 10.1016/0009-8981(68)90114-9. [DOI] [PubMed] [Google Scholar]
  21. Blainey J. D., Northam B. E. Amylase excretion by the human kidney. Clin Sci. 1967 Jun;32(3):377–383. [PubMed] [Google Scholar]
  22. Block M. B., Genant H. K., Kirsner J. B. Pancreatitis as an adverse reaction to salicylazosulfapyridine. N Engl J Med. 1970 Feb 12;282(7):380–382. doi: 10.1056/NEJM197002122820710. [DOI] [PubMed] [Google Scholar]
  23. Bock O. A. A comment on the use of anticholinergics in the management of acute pancreatitis. S Afr Med J. 1968 Aug 31;42(33):859–860. [PubMed] [Google Scholar]
  24. Bolooki H., Gliedman M. L. Peritoneal dialysis in treatment of acute pancreatitis. Surgery. 1968 Aug;64(2):466–471. [PubMed] [Google Scholar]
  25. Bolooki H., Jaffe B., Gliedman M. L. Pancreatic abscesses and lesser omental sac collections. Surg Gynecol Obstet. 1968 Jun;126(6):1301–1308. [PubMed] [Google Scholar]
  26. Boyd J. F. Salmonella typhimurium, colitis, and pancreatitis. Lancet. 1969 Oct 25;2(7626):901–902. doi: 10.1016/s0140-6736(69)92352-6. [DOI] [PubMed] [Google Scholar]
  27. Bronsky D., Weisbery M. G., Gross M. C., Barton J. J. Hyperparathyroidism and acute postpartum pancreatitis with neonatal tetany in the child. Am J Med Sci. 1970 Sep;260(3):160–164. doi: 10.1097/00000441-197009000-00003. [DOI] [PubMed] [Google Scholar]
  28. COMFORT M. W., GROSS J. B. Chronic pancreatitis. Am J Med. 1956 Oct;21(4):596–617. doi: 10.1016/0002-9343(56)90075-4. [DOI] [PubMed] [Google Scholar]
  29. Cameron J. L., Crisler C., Margolis S., DeMeester T. R., Zuidema G. D. Acute pancreatitis with hyperlipemia. Surgery. 1971 Jul;70(1):53–61. [PubMed] [Google Scholar]
  30. Carter E. A., Drummey G. D., Isselbacher K. J. Ethanol stimulates triglyceride synthesis by the intestine. Science. 1971 Dec 17;174(4015):1245–1247. doi: 10.1126/science.174.4015.1245. [DOI] [PubMed] [Google Scholar]
  31. Catanzaro F. P., Abiri M., Allegra S. Spontaneous rupture of spleen and pleural effusion complicating pancreatitis. R I Med J. 1968 May;51(5):328–329. [PubMed] [Google Scholar]
  32. Ceska M., Birath K., Brown B. A new and rapid method for the clinical determination of alpha-amylase activities in human serum and urine. Optimal conditions. Clin Chim Acta. 1969 Dec;26(3):437–444. doi: 10.1016/0009-8981(69)90071-0. [DOI] [PubMed] [Google Scholar]
  33. Clayman S., Swaminathan C. V., Scholefield P. G. Transport and exchange diffusion of amino acids by in vitro preparations of pancreas from normal, tumor-bearing and alcohol-treated mice. Biochem Biophys Res Commun. 1968 May 23;31(4):553–557. doi: 10.1016/0006-291x(68)90513-5. [DOI] [PubMed] [Google Scholar]
  34. Cogbill C. L., Song K. T. Acute pancreatitis. Arch Surg. 1970 Jun;100(6):673–676. doi: 10.1001/archsurg.1970.01340240041008. [DOI] [PubMed] [Google Scholar]
  35. Collins J. J., Jr, Peterson L. M., Wilson R. E. Small intestinal infarction as a complication of pancreatitis. Ann Surg. 1968 Mar;167(3):433–436. doi: 10.1097/00000658-196803000-00019. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Creutzfeldt W., Schmidt H. Aetiology and pathogenesis of pancreatitis. (Current concepts). Scand J Gastroenterol Suppl. 1970;6:47–62. [PubMed] [Google Scholar]
  37. Dalton W. E., Lee H. M., Williams G. M., Hume D. M. Pancreatic pseudocyst causing hemobilia and massive gastrointestinal hemorrhage. Am J Surg. 1970 Jul;120(1):106–107. doi: 10.1016/s0002-9610(70)80158-1. [DOI] [PubMed] [Google Scholar]
  38. Dardik I., Dardik H. Patterns of hemorrhage into pancreatic pseudocysts. Am J Surg. 1968 Jun;115(6):774–776. doi: 10.1016/0002-9610(68)90517-5. [DOI] [PubMed] [Google Scholar]
  39. Darle N., Ekholm R., Edlund Y. Ultrastructure of the rat exocrine pancreas after long term intake of ethanol. Gastroenterology. 1970 Jan;58(1):62–72. [PubMed] [Google Scholar]
  40. Davidson P., Costanza D., Swieconek J. A., Harris J. B. Hereditary pancreatitis. A kindred without gross aminoaciduria. Ann Intern Med. 1968 Jan;68(1):88–96. doi: 10.7326/0003-4819-68-1-88. [DOI] [PubMed] [Google Scholar]
  41. Diaco J. F., Miller L. D., Copeland E. M. The role of early diagnostic laparotomy in acute pancreatitis. Surg Gynecol Obstet. 1969 Aug;129(2):263–269. [PubMed] [Google Scholar]
  42. Dixon J. A., Hillam J. D. Surgical treatment of biliary tract disease associated with acute pancreatitis. Am J Surg. 1970 Sep;120(3):371–375. [PubMed] [Google Scholar]
  43. Dyck W. P., Rudick J., Hoexter B., Janowitz H. D. Influence of glucagon on pancreatic exocrine secretion. Gastroenterology. 1969 Mar;56(3):531–537. [PubMed] [Google Scholar]
  44. Dyck W. P., Texter E. C., Jr, Lasater J. M., Hightower N. C., Jr Influence of glucagon on pancreatic exocrine secretion in man. Gastroenterology. 1970 Apr;58(4):532–539. [PubMed] [Google Scholar]
  45. Economou G., Ward-McQuaid J. N. A cross-over comparison of the effect of morphine, pethidine, pentazocine, and phenazocine on biliary pressure. Gut. 1971 Mar;12(3):218–221. doi: 10.1136/gut.12.3.218. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Eisenbaum S., Grant R. N., Cohen A. Hemorrhagic pseudocyst with pancreatitis in a ten-year-old boy. Am Surg. 1970 Jun;36(6):387–388. [PubMed] [Google Scholar]
  47. Evans F. C. Pancreatic abscess. Am J Surg. 1969 Apr;117(4):537–540. doi: 10.1016/0002-9610(69)90013-0. [DOI] [PubMed] [Google Scholar]
  48. FREDRICKSON D. S., ONO K., DAVIS L. L. LIPOLYTIC ACTIVITY OF POST-HEPARIN PLASMA IN HYPERGLYCERIDEMIA. J Lipid Res. 1963 Jan;4:24–33. [PubMed] [Google Scholar]
  49. Facey F. L., Weil M. H., Rosoff L. Mechanism and treatment of shock associated with acute pancreatitis. Am J Surg. 1966 Mar;111(3):374–381. doi: 10.1016/s0002-9610(66)80015-6. [DOI] [PubMed] [Google Scholar]
  50. Finley J. W. Respiratory complications of acute pancatitis. Am Surg. 1969 Aug;35(8):591–598. [PubMed] [Google Scholar]
  51. Fleisher M., Schwartz M. K. An automated, fluorometric procedure for determining serum lipase. Clin Chem. 1971 May;17(5):417–422. [PubMed] [Google Scholar]
  52. Flemma R. J., Flint L. M., Osterhout S., Shingleton W. W. Bacteriologic studies of biliary tract infection. Ann Surg. 1967 Oct;166(4):563–572. doi: 10.1097/00000658-196710000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  53. Frey C. F., Bradley D. M., Glore J., Wanner J. Hematin formation and pancreatitis. J Surg Res. 1969 Feb;9(2):73–78. doi: 10.1016/0022-4804(69)90034-1. [DOI] [PubMed] [Google Scholar]
  54. Frey C. F. The operative treatment of pancreatitis. Arch Surg. 1969 Apr;98(4):406–417. doi: 10.1001/archsurg.1969.01340100038003. [DOI] [PubMed] [Google Scholar]
  55. GROSS J. B., GAMBILL E. E., ULRICH J. A. Hereditary pancreatitis. Description of a fifth kindred and summary of clinical features. Am J Med. 1962 Sep;33:358–364. doi: 10.1016/0002-9343(62)90232-2. [DOI] [PubMed] [Google Scholar]
  56. GROSS J. B., ULRICH J. A., JONES J. D. URINARY EXCRETION OF AMINO ACIDS IN A KINDRED WITH HEREDITARY PANCREATITIS AND AMINOACIDURIA. Gastroenterology. 1964 Jul;47:41–48. [PubMed] [Google Scholar]
  57. Gabryelewicz A., Niewiarowski S. Activation of blood clotting and inhibition of fibrinolysis in acute pancreatitis. Thromb Diath Haemorrh. 1968 Dec 31;20(3):409–414. [PubMed] [Google Scholar]
  58. Gambill E. E. Pancreatitis associated with pancreatic carcinoma: a study of 26 cases. Mayo Clin Proc. 1971 Mar;46(3):174–177. [PubMed] [Google Scholar]
  59. Gee W., Foster E. D., Doohen D. J. Mediastinal pancreatic pseudocyst. Ann Surg. 1969 Mar;169(3):420–424. doi: 10.1097/00000658-196903000-00017. [DOI] [PMC free article] [PubMed] [Google Scholar]
  60. Geokas M. C., Murphy R., McKenna R. D. The role of elastase in acute pancreatitis. I. Intrapancreatic elastolytic activity in bile-induced acute pancreatitis in dogs. Arch Pathol. 1968 Aug;86(2):117–126. [PubMed] [Google Scholar]
  61. Geokas M. C. The role of elastase in acute pancreatitis. II. Intrapancreatic elastolytic activity in trypsin-induced acute pancreatitis in dogs. Arch Pathol. 1968 Aug;86(2):127–134. [PubMed] [Google Scholar]
  62. Geokas M. C., Van Lancker J. L., Kadell B. M., Machleder H. I. Acute pancreatitis. Ann Intern Med. 1972 Jan;76(1):105–117. doi: 10.7326/0003-4819-76-1-105. [DOI] [PubMed] [Google Scholar]
  63. Giacobino J. P., Simon G. T. Experimental glomerulonephritis induced by minimal doses of trypsin. Arch Pathol. 1971 Mar;91(3):193–200. [PubMed] [Google Scholar]
  64. Gjessing J. Peritoneal dialysis in severe acute hemorrhagic pancreatitis. Acta Chir Scand. 1967;133(8):645–647. [PubMed] [Google Scholar]
  65. Goodhead B. Acute pancreatitis and pancreatic blood flow. Surg Gynecol Obstet. 1969 Aug;129(2):331–340. [PubMed] [Google Scholar]
  66. Goodhead B. Significance of methemalbuminemia in acute abdominal emergencies. Arch Surg. 1970 Sep;101(3):376–378. doi: 10.1001/archsurg.1970.01340270024006. [DOI] [PubMed] [Google Scholar]
  67. Goodhead B., Wright P. W. The effect of postganglionic sympathectomy on the development of hemorrhagic pancreatitis in the dog. Ann Surg. 1969 Dec;170(6):951–960. doi: 10.1097/00000658-196912000-00015. [DOI] [PMC free article] [PubMed] [Google Scholar]
  68. Gottfries A., Nilsson S., Samuelsson B., Scherstén T. Phospholipids in human hepatic bile, gall bladder bile, and plasma in cases with acute cholecystitis. Scand J Clin Lab Invest. 1968;21(2):168–176. doi: 10.3109/00365516809084279. [DOI] [PubMed] [Google Scholar]
  69. Greene L. J., Rigbi M., Fackre D. S. Trypsin inhibitor from bovine pancreatic juice. J Biol Chem. 1966 Dec 10;241(23):5610–5618. [PubMed] [Google Scholar]
  70. Greenstein A., DeMaio E. F., Nabseth D. C. Acute hemorrhage associated with pancreatic pseudocysts. Surgery. 1971 Jan;69(1):56–62. [PubMed] [Google Scholar]
  71. Griffen W. O., Jr, Schaefer J. W., Schindler S., Hyde G., Bryant L. R. Ampullary obstruction by benign duodenal polyps. Arch Surg. 1968 Sep;97(3):444–449. doi: 10.1001/archsurg.1968.01340030104009. [DOI] [PubMed] [Google Scholar]
  72. Griffiths R. W., Brown P. W., Jr Jejunal infarction as a complication of pancreatitis. Gastroenterology. 1970 May;58(5):709–712. [PubMed] [Google Scholar]
  73. Guerrier K., Persky L. Pancreatic disease simulating renal abnormality. Am J Surg. 1970 Jul;120(1):46–49. doi: 10.1016/s0002-9610(70)80142-8. [DOI] [PubMed] [Google Scholar]
  74. Guyer P. B., Amin P. H. Radiological demonstration of spontaneous rupture of pancreatic pseudo-cysts. Br J Radiol. 1970 May;43(509):342–343. doi: 10.1259/0007-1285-43-509-342. [DOI] [PubMed] [Google Scholar]
  75. Gülzow M., Diwok K., Trettin H. J. Die experimentelle Kalziumpankreatitis der Ratte. Z Gesamte Inn Med. 1965 Nov 15;20(22):673–678. [PubMed] [Google Scholar]
  76. HERSKOVIC T., WAKIM K. G., BARTHOLOMEW L. G., CAIN J. C., JONES J. D. RELATIONSHIP OF CALCIUM IN THE SERUM TO THAT IN THE PANCREATIC SECRETION IN NORMAL AND HYPERCALCEMIC STATES. Surgery. 1965 Sep;58:530–534. [PubMed] [Google Scholar]
  77. HOLLAND J. F., DANIELSON E., SAHAGIAN-EDWARDS A. Use of ethylene diamine tetra acetic acid in hypercalcemic patients. Proc Soc Exp Biol Med. 1953 Nov;84(2):359–364. doi: 10.3181/00379727-84-20645. [DOI] [PubMed] [Google Scholar]
  78. Hagen P. O., Ofstad E., Amundsen E. Experimental acute pancreatitis in dogs. 3. The nature of the phospholipase activity of pancreatic exudate. Scand J Gastroenterol. 1969;4(1):81–88. doi: 10.3109/00365526909180154. [DOI] [PubMed] [Google Scholar]
  79. Hansky J. Calcium content of duodenal juice. Am J Dig Dis. 1967 Jul;12(7):725–733. doi: 10.1007/BF02238282. [DOI] [PubMed] [Google Scholar]
  80. Hansky J. The use of a peptidase inhibitor in the treatment of acute pancreatitis. Med J Aust. 1969 Jun 21;1(25):1284–1285. doi: 10.5694/j.1326-5377.1969.tb62351.x. [DOI] [PubMed] [Google Scholar]
  81. Hansson K. Experimental and clinical studies in aetiologic role of bile reflux in acute pancreatitis. Acta Chir Scand Suppl. 1967;375:102–102. [PubMed] [Google Scholar]
  82. Hansson K., Lenninger S. Proteinase inhibitors in acute pancreatitis. Acta Chir Scand Suppl. 1967;378:103–114. [PubMed] [Google Scholar]
  83. Harjola P. T., Siltanen P., Appelqvist P., Laustela E. Abdominal complications after open heart surgery. Ann Chir Gynaecol Fenn. 1968;57(3):272–274. [PubMed] [Google Scholar]
  84. Hathaway J. A., Hunter D. T., Berrett C. R. An automated method for the determination of amylase. Clin Biochem. 1970 Sep;3(3):217–224. [PubMed] [Google Scholar]
  85. Hermann R. E., Hertzer N. R. Time of biliary surgery after acute pancreatitis due to biliary disease. Arch Surg. 1970 Jan;100(1):71–75. doi: 10.1001/archsurg.1970.01340190073016. [DOI] [PubMed] [Google Scholar]
  86. Herva P. Experimental biliary pancreatitis in dogs. Demonstration of proteolytic activity in pancreatic tissue extracts and interference of dog serum constituents with proteolytic enzymes. Introduction. Scand J Gastroenterol Suppl. 1970;8:9–13. [PubMed] [Google Scholar]
  87. Hiatt N., Warner N. E. Serum amylase and changes in pancreatic function and structure after ligation of pancreatic ducts. Am Surg. 1969 Jan;35(1):30–35. [PubMed] [Google Scholar]
  88. Hooper J. C., Stoker T. A. Rupture of the oesophagus associated with acute pancreatitis. Br J Clin Pract. 1970 Nov;24(11):481–484. [PubMed] [Google Scholar]
  89. Horton E. H., Murthy S. K., Seal R. M. Haemorrhagic necrosis of small intestine and acute pancreatitis following open-heart surgery. Thorax. 1968 Jul;23(4):438–445. doi: 10.1136/thx.23.4.438. [DOI] [PMC free article] [PubMed] [Google Scholar]
  90. Iseri O. A., Lieber C. S., Gottlieb L. S. The ultrastructure of fatty liver induced by prolonged ethanol ingestion. Am J Pathol. 1966 Apr;48(4):535–555. [PMC free article] [PubMed] [Google Scholar]
  91. Joffe B. I., Bank S., Jackson W. P., Keller P., O'Reilly I. G., Vinik A. I. Insulin reserve in patients with chronic pancreatitis. Lancet. 1968 Oct 26;2(7574):890–892. doi: 10.1016/s0140-6736(68)91055-6. [DOI] [PubMed] [Google Scholar]
  92. Joffe B. I., Bank S., Jackson W. P., Vinik A. I., Keller P. Effect of intravenous tolbutamide on serum insulin levels in pancreatic diabetes. Diabetes. 1969 Jul;18(7):499–501. doi: 10.2337/diab.18.7.499. [DOI] [PubMed] [Google Scholar]
  93. Joffe B. I., Bank S., Marks I. N. Hypoglycaemia in pancreatitis. Lancet. 1968 Nov 9;2(7576):1038–1038. doi: 10.1016/s0140-6736(68)91333-0. [DOI] [PubMed] [Google Scholar]
  94. Johnson W. C., Nabseth D. C. Pancreatitis in renal transplantation. Ann Surg. 1970 Feb;171(2):309–314. doi: 10.1097/00000658-197002000-00022. [DOI] [PMC free article] [PubMed] [Google Scholar]
  95. Jones S. A., Steedman R. A., Keller T. B., Smith L. L. Transduodenal sphincteroplasty (not sphincterotomy) for biliary and pancreatic disease. Indications, contraindications, and results. Am J Surg. 1969 Aug;118(2):292–306. doi: 10.1016/0002-9610(69)90132-9. [DOI] [PubMed] [Google Scholar]
  96. KELLER P. J., COHEN E., NEURATH H. The proteins of bovine pancreatic juice. J Biol Chem. 1958 Aug;233(2):344–349. [PubMed] [Google Scholar]
  97. KESSLER J. I., KNIFFEN J. C., JANOWITZ H. D. LIPOPROTEIN LIPASE INHIBITION IN THE HYPERLIPEMIA OF ACUTE ALCOHOLIC PANCREATITIS. N Engl J Med. 1963 Oct 31;269:943–948. doi: 10.1056/NEJM196310312691803. [DOI] [PubMed] [Google Scholar]
  98. KUKRAL J. C., ADAMS A. P., PRESTON F. W. PROTEIN PRODUCING CAPACITY OF THE HUMAN EXOCRINE PANCREAS: INCORPORATION OF S35 METHIONINE IN SERUM AND PANCREATIC JUICE PROTEIN. Ann Surg. 1965 Jul;162:63–73. doi: 10.1097/00000658-196507000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  99. Kalant H. Alcohol, pancreatic secretion, and pancreatitis. Gastroenterology. 1969 Feb;56(2):380–384. [PubMed] [Google Scholar]
  100. Karmody A. M., Galloway J. M. Haemorrhagic shock in early acute pancreatitis. A rare but significant event. Br J Surg. 1971 Jul;58(7):519–520. doi: 10.1002/bjs.1800580713. [DOI] [PubMed] [Google Scholar]
  101. Katz L. A., Spiro H. M. Gastrointestinal manifestations of diabetes. N Engl J Med. 1966 Dec 15;275(24):1350–1361. doi: 10.1056/NEJM196612152752406. [DOI] [PubMed] [Google Scholar]
  102. Keighley M. R., Johnson A. G., Stevens A. E. Raised serum amylase after upper abdominal operation. Br J Surg. 1969 Jun;56(6):424–427. doi: 10.1002/bjs.1800560606. [DOI] [PubMed] [Google Scholar]
  103. Keller P. J., Allan B. J. The protein composition of human pancreatic juice. J Biol Chem. 1967 Jan 25;242(2):281–287. [PubMed] [Google Scholar]
  104. Kelly T. R. Relationship of hyperparathyroidism to pancreatitis. Arch Surg. 1968 Aug;97(2):267–274. doi: 10.1001/archsurg.1968.01340020131016. [DOI] [PubMed] [Google Scholar]
  105. Kewenter J., Kock N. G. The effect of some spasmolytic drugs on the choledocho-duodenal junction in man. Scand J Gastroenterol. 1971;6(5):401–405. doi: 10.3109/00365527109180716. [DOI] [PubMed] [Google Scholar]
  106. Klein B., Foreman J. A., Searcy R. L. New chromogenic substrate for determination of serum amylase activity. Clin Chem. 1970 Jan;16(1):32–38. [PubMed] [Google Scholar]
  107. Knight M. J., Condon J. R., Smith R. Possible use of glucagon in the treatment of pancreatitis. Br Med J. 1971 May 22;2(5759):440–442. doi: 10.1136/bmj.2.5759.440. [DOI] [PMC free article] [PubMed] [Google Scholar]
  108. Konok G. P., Thompson A. G. Pancreatic ductal mucosa as a protective barrier in the pathogenesis of pancreatitis. Am J Surg. 1969 Jan;117(1):18–23. doi: 10.1016/0002-9610(69)90280-3. [DOI] [PubMed] [Google Scholar]
  109. Kudzma D. J., Schonfeld G. Alcoholic hyperlipidemia: induction by alcohol but not by carbohydrate. J Lab Clin Med. 1971 Mar;77(3):384–395. [PubMed] [Google Scholar]
  110. Kune G. A. Abscesses of the pancreas. Aust N Z J Surg. 1968 Nov;38(2):125–128. [PubMed] [Google Scholar]
  111. LAGERGREN C. Calcium carbonate precipitation in the pancreas, gallstones and urinary calculi. Acta Chir Scand. 1962 Oct;124:320–325. [PubMed] [Google Scholar]
  112. LOSOWSKY M. S., JONES D. P., DAVIDSON C. S., LIEBER C. S. STUDIES OF ALCOHOLIC HYPERLIPEMIA AND ITS MECHANISM. Am J Med. 1963 Dec;35:794–803. doi: 10.1016/0002-9343(63)90241-9. [DOI] [PubMed] [Google Scholar]
  113. Landman H., Markwardt F., Perlewitz J. Die Beeinflussung der Wirkung des Trypsins auf die Blutgerinnung durch natürliche und synthetische Trypsin- und Thrombininhibitoren. Thromb Diath Haemorrh. 1969 Dec 31;22(3):552–568. [PubMed] [Google Scholar]
  114. Lawrence A. M. Radioimmunoassayable glucagon levels in man: effects of starvation, hypoglycemia, and glucose administration. Proc Natl Acad Sci U S A. 1966 Feb;55(2):316–320. doi: 10.1073/pnas.55.2.316. [DOI] [PMC free article] [PubMed] [Google Scholar]
  115. Lawson D. W., Daggett W. M., Civetta J. M., Corry R. J., Bartlett M. K. Surgical treatment of acute necrotizing pancreatitis. Ann Surg. 1970 Oct;172(4):605–617. doi: 10.1097/00000658-197010000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  116. Legge D. A., Hoffman H. N., 2nd, Carlson H. C. Pancreatitis as a complication of regional enteritis of the duodenum. Gastroenterology. 1971 Dec;61(6):834–837. [PubMed] [Google Scholar]
  117. Levitt M. D., Rapoport M., Cooperband S. R. The renal clearance of amylase in renal insufficiency, acute pancreatitis, and macroamylasemia. Ann Intern Med. 1969 Nov;71(5):919–925. doi: 10.7326/0003-4819-71-5-919. [DOI] [PubMed] [Google Scholar]
  118. Levy R. I., Fredrickson D. S. Diagnosis and management of hyperlipoproteinemia. Am J Cardiol. 1968 Oct;22(4):576–583. doi: 10.1016/0002-9149(68)90165-3. [DOI] [PubMed] [Google Scholar]
  119. Logan A., Jr, Schlicke C. P., Manning G. B. Familial pancreatitis. Am J Surg. 1968 Jan;115(1):112–117. doi: 10.1016/0002-9610(68)90138-4. [DOI] [PubMed] [Google Scholar]
  120. MINKOWITZ S., SOLOWAY H. B., HALL J. E., YERMAKOV V. FATAL HEMORRHAGIC PANCREATITIS FOLLOWING CHLOROTHIAZIDE ADMINISTRATION IN PREGNANCY. Obstet Gynecol. 1964 Sep;24:337–342. doi: 10.1097/00006250-196409000-00002. [DOI] [PubMed] [Google Scholar]
  121. Mayday G. B., Pheils M. T. Pancreatitis: a clinical review. Med J Aust. 1970 Jun 6;1(23):1142–1144. doi: 10.5694/j.1326-5377.1970.tb84479.x. [DOI] [PubMed] [Google Scholar]
  122. McCutcheon A. D. A fresh approach to the pathogenesis of pancreatitis. Gut. 1968 Jun;9(3):296–310. doi: 10.1136/gut.9.3.296. [DOI] [PMC free article] [PubMed] [Google Scholar]
  123. Merikas G., Stathopoulos G., Katsas A. Painless pancreatic pseudocyst ruptured into the thoracic cavity. Gastroenterology. 1968 Jan;54(1):101–104. [PubMed] [Google Scholar]
  124. Mohiuddin S., Sakiyalak P., Gullick H. D., Webb W. R. Stenosing lesions of the colon secondary to pancreatitis. Arch Surg. 1971 Mar;102(3):229–231. doi: 10.1001/archsurg.1971.01350030067022. [DOI] [PubMed] [Google Scholar]
  125. Montgomery W. H., Miller F. C. Pancreatitis and pregnancy. Obstet Gynecol. 1970 Apr;35(4):658–664. [PubMed] [Google Scholar]
  126. Muldowney F. P., McKenna T. J., Kyle L. H., Freaney R., Swan M. Parathormone-like effect of magnesium replenishment in steatorrhea. N Engl J Med. 1970 Jan 8;282(2):61–68. doi: 10.1056/NEJM197001082820203. [DOI] [PubMed] [Google Scholar]
  127. Mulhausen R., Brown D. C., Onstad G. Renal clearance of amylase during pancreatitis. Metabolism. 1969 Aug;18(8):669–674. doi: 10.1016/0026-0495(69)90080-8. [DOI] [PubMed] [Google Scholar]
  128. Musella S., Alfano C., Ciardiello A., De' Longis G. Considerazioni su di un raro caso di pancreatite acuta consecutiva ad un iperdosaggio di preparati cortisonici. Rass Int Clin Ter. 1971 Apr 15;51(7):400–407. [PubMed] [Google Scholar]
  129. NEURATH H. MECHANISM OF ZYMOGEN ACTIVATION. Fed Proc. 1964 Jan-Feb;23:1–7. [PubMed] [Google Scholar]
  130. Nakajima S., Magee D. F. Inhibition of exocrine pancreatic secretion by glucagon and D-glucose given intravenously. Can J Physiol Pharmacol. 1970 May;48(5):299–305. doi: 10.1139/y70-049. [DOI] [PubMed] [Google Scholar]
  131. Nimmo J., Finlayson N. D., Smith A. F., Shearman D. J. The production of calcium and magnesium during pancreatic function tests in health and disease. Gut. 1970 Feb;11(2):163–166. doi: 10.1136/gut.11.2.163. [DOI] [PMC free article] [PubMed] [Google Scholar]
  132. Ofstad E., Amundsen E., Hagen P. O. Experimental acute pancreatitis in dogs. II. Histamine release induced by pancreatic exudate. Scand J Gastroenterol. 1969;4(1):75–79. doi: 10.3109/00365526909180153. [DOI] [PubMed] [Google Scholar]
  133. Ofstad E. Formation and destruction of plasma kinins during experimental acute hemorrhagic pancreatitis in dogs. Scand J Gastroenterol Suppl. 1970;5:1–44. [PubMed] [Google Scholar]
  134. Orrego-Matte H., Navia E., Feres A., Costamaillere L. Ethanol ingestion and incorporation of 32P into phospholipids of pancreas in the rat. Gastroenterology. 1969 Feb;56(2):280–285. [PubMed] [Google Scholar]
  135. PAPPENHEIMER A. M., KUNZ L. J., RICHARDSON S. Passage of Coxsackie virus (Connecticut-5 strain) in adult mice with production of pancreatic disease. J Exp Med. 1951 Jul 1;94(1):45–64. doi: 10.1084/jem.94.1.45. [DOI] [PMC free article] [PubMed] [Google Scholar]
  136. PLATT H. The occurrence of pancreatic lesions in adult mice infected with the virus of foot-and-mouth disease. Virology. 1959 Nov;9:484–486. doi: 10.1016/0042-6822(59)90139-4. [DOI] [PubMed] [Google Scholar]
  137. PROBSTEIN J. G., JOSHI R. A., BLUMENTHAL H. T. Atheromatous embolization; an etiology of acute pancreatitis. AMA Arch Surg. 1957 Oct;75(4):566–572. [PubMed] [Google Scholar]
  138. Paloyan D., Paloyan E., Worobec R., Ernst K., Deininger E., Harper P. V. Serum glucagon levels in experimental acute pancreatitis in the dog. Surg Forum. 1966;17:348–349. [PubMed] [Google Scholar]
  139. Paloyan E., Paloyan D., Harper P. V. Glucagon-induced hypocalcemia. Metabolism. 1967 Jan;16(1):35–39. doi: 10.1016/0026-0495(67)90156-4. [DOI] [PubMed] [Google Scholar]
  140. Panebianco A. C., Scott S. M., Dart C. H., Jr, Takaro T., Echegaray H. M. Acute pancreatitis following extrorporeal circulation. Ann Thorac Surg. 1970 Jun;9(6):562–568. doi: 10.1016/s0003-4975(10)65551-8. [DOI] [PubMed] [Google Scholar]
  141. Peterson L. M., Collins J. J., Jr, Wilson R. E. Acute pancreatitis occurring after operation. Surg Gynecol Obstet. 1968 Jul;127(1):23–28. [PubMed] [Google Scholar]
  142. Pirola R. C., Bolin T. D., Davis A. E. Does alcohol cause duodenitis? Am J Dig Dis. 1969 Apr;14(4):239–244. doi: 10.1007/BF02235952. [DOI] [PubMed] [Google Scholar]
  143. Pirola R. C., Davis A. E. Effects of ethyl alcohol on sphincteric resistance at the choledocho-duodenal junction in man. Gut. 1968 Oct;9(5):557–560. doi: 10.1136/gut.9.5.557. [DOI] [PMC free article] [PubMed] [Google Scholar]
  144. Pirola R. C., Davis A. E. Effects of intravenous alcohol on motility of the duodenum and of the sphincter of Oddi. Australas Ann Med. 1970 Feb;19(1):24–29. doi: 10.1111/imj.1970.19.1.24. [DOI] [PubMed] [Google Scholar]
  145. Pratt C. B., Simone J. V., Zee P., Aur R. J., Johnson W. W. Comparison of daily versus weekly L-asparaginase for the treatment of childhood acute leukemia. J Pediatr. 1970 Sep;77(3):474–483. doi: 10.1016/s0022-3476(70)80023-3. [DOI] [PubMed] [Google Scholar]
  146. Riemenschneider T. A., Wilson J. F., Vernier R. L. Glucocorticoid-induced pancreatitis in children. Pediatrics. 1968 Feb;41(2):428–437. [PubMed] [Google Scholar]
  147. Rinderknecht H., Marbach E. P. A new automated method for the determination of serum alpha-amylase. Clin Chim Acta. 1970 Jul;29(1):107–110. doi: 10.1016/0009-8981(70)90230-5. [DOI] [PubMed] [Google Scholar]
  148. Rinderknecht H., Silverman P., Geokas M. C. Investigations on the standardization, assay and action of elastase. Enzymologia. 1971 Jun 30;40(6):345–359. [PubMed] [Google Scholar]
  149. Rinderknecht H., Wilding P., Haverback B. J. A new method for the determination of alpha-amylase. Experientia. 1967 Oct 15;23(10):805–805. doi: 10.1007/BF02146851. [DOI] [PubMed] [Google Scholar]
  150. Rogers J. B., Howard J. M., Pairent F. W. Serum insulin levels in patients with chronic pancreatitis. Am J Surg. 1970 Feb;119(2):171–176. doi: 10.1016/0002-9610(70)90029-2. [DOI] [PubMed] [Google Scholar]
  151. Rubin E., Beattie D. S., Lieber C. S. Effects of ethanol on the biogenesis of mitochondrial membranes and associated mitochondrial functions. Lab Invest. 1970 Dec;23(6):620–627. [PubMed] [Google Scholar]
  152. Rudyi R. V., Chaplinskii V. V. Insulinovaia aktivnost' plazmy krovi bol'nykh razlichnymi formani ostrogo pankreatita. Klin Med (Mosk) 1965 Nov;43(11):77–82. [PubMed] [Google Scholar]
  153. SHINOWARA G. Y., STUTMAN L. J., WALTERS M. I., RUTH M. E., WALKER E. J. Hypercoagulability in acute pancreatitis. Am J Surg. 1963 Jun;105:714–719. doi: 10.1016/0002-9610(63)90483-5. [DOI] [PubMed] [Google Scholar]
  154. Sardesai V. M., Orten J. M. Effect of prolonged alcohol consumption in rats on pancreatic protein synthesis. J Nutr. 1968 Oct;96(2):241–246. doi: 10.1093/jn/96.2.241. [DOI] [PubMed] [Google Scholar]
  155. Schapiro H., Wruble L. D., Britt L. G. The possible mechanism of alcohol in the production of acute pancreatitis. Surgery. 1966 Nov;60(5):1108–1111. [PubMed] [Google Scholar]
  156. Scharf Y., Better O., Gellei B., Hemli J., Peled B., Brandstaetter S. Long-standing recurrent pancreatitis as manifested in parathyroid carcinoma. Am J Gastroenterol. 1969 Aug;52(2):111–115. [PubMed] [Google Scholar]
  157. Schmidt H., Creutzfeldt W. Calciphylactic pancreatitis and pancreatitis in hyperparathyroidism. Clin Orthop Relat Res. 1970 Mar-Apr;69:135–145. [PubMed] [Google Scholar]
  158. Schmidt H., Creutzfeldt W., Habermann E. Phospholipase A--ein möglicherweise entscheidender Faktor in der Pathogenese de akuten Pankreatitis. Klin Wochenschr. 1967 Feb 1;45(3):163–164. doi: 10.1007/BF01725076. [DOI] [PubMed] [Google Scholar]
  159. Schmidt H., Creutzfeldt W. The possible role of phospholipase A in the pathogenesis of acute pancreatitis. Scand J Gastroenterol. 1969;4(1):39–48. doi: 10.3109/00365526909180149. [DOI] [PubMed] [Google Scholar]
  160. Seward C. W. Diagnosing pancreatitis the first day: a comparison of urinary amylase and serum enzymes in pancreatic dysfunction. South Med J. 1970 Mar;63(3):286–289. doi: 10.1097/00007611-197003000-00009. [DOI] [PubMed] [Google Scholar]
  161. Sharf B., Bental E. Pancreatic encephalopathy. J Neurol Neurosurg Psychiatry. 1971 Jun;34(3):357–361. doi: 10.1136/jnnp.34.3.357. [DOI] [PMC free article] [PubMed] [Google Scholar]
  162. Shaw M. T., Barnes C. C., Madden F. J., Bagshawe K. D. L-asparaginase and pancreatitis. Lancet. 1970 Oct 3;2(7675):721–721. doi: 10.1016/s0140-6736(70)91990-2. [DOI] [PubMed] [Google Scholar]
  163. Sherins R. J., Verity M. A. Central pontine myelinolysis associated with acute haemorrhagic pancreatitis. J Neurol Neurosurg Psychiatry. 1968 Dec;31(6):583–588. doi: 10.1136/jnnp.31.6.583. [DOI] [PMC free article] [PubMed] [Google Scholar]
  164. Sherwood L. M. Magnesium ion and parathyroid function. N Engl J Med. 1970 Mar 26;282(13):752–752. doi: 10.1056/NEJM197003262821315. [DOI] [PubMed] [Google Scholar]
  165. Skinner D. B., Corson J. G., Nardi G. L. Aprotinin therapy as prophylaxis against postoperative pancreatitis in humans. A controlled evaluation. JAMA. 1968 Jun 10;204(11):945–948. [PubMed] [Google Scholar]
  166. Stern P. H., Bell N. H. Effects of glucagon on serum calcium in the rat and on bone resorption in tissue culture. Endocrinology. 1970 Jul;87(1):111–117. doi: 10.1210/endo-87-1-111. [DOI] [PubMed] [Google Scholar]
  167. Stobbe K. C., ReMine W. H., Baggenstoss A. H. Pancreatic lithiasis. Surg Gynecol Obstet. 1970 Dec;131(6):1090–1099. [PubMed] [Google Scholar]
  168. Strum W. B., Spiro H. M. Chronic pancreatitis. Ann Intern Med. 1971 Feb;74(2):264–277. doi: 10.7326/0003-4819-74-2-264. [DOI] [PubMed] [Google Scholar]
  169. Tashijan A. H., Jr, Howland B. G., Melvin K. E., Hill C. S., Jr Immunoassay of human calcitonin. N Engl J Med. 1970 Oct 22;283(17):890–895. doi: 10.1056/NEJM197010222831702. [DOI] [PubMed] [Google Scholar]
  170. Tegenfeldt E. G., Kirtland H. B., Brown R. G. Gallstones, pancreatitis and pregnancy. Am Surg. 1967 Jan;33(1):88–90. [PubMed] [Google Scholar]
  171. Thorpe M. E., Shorey C. D. Long-term alcohol administration. Its effects on the ultrastructure and lipid content of the rat liver cell. Am J Pathol. 1966 Apr;48(4):557–577. [PMC free article] [PubMed] [Google Scholar]
  172. Trapnell J. E., Anderson M. C. Role of early laparotomy in acute pancreatitis. Ann Surg. 1967 Jan;165(1):49–55. doi: 10.1097/00000658-196701000-00006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  173. Travis J., Roberts R. C. Human trypsin. Isolation and physical-chemical characterization. Biochemistry. 1969 Jul;8(7):2884–2889. doi: 10.1021/bi00835a029. [DOI] [PubMed] [Google Scholar]
  174. Trowbridge J. O., Moon H. D. Elastase in human pancreas. Immunologic and fluorescent antibody studies. Lab Invest. 1969 Oct;21(4):288–291. [PubMed] [Google Scholar]
  175. Vestad E., Aakhus T. Acute pancreatitis. Intra-arterial treatment with trasylol. Acta Chir Scand. 1970;136(2):147–151. [PubMed] [Google Scholar]
  176. WATTS G. T. TOTAL PANCREATECTOMY FOR FULMINANT PANCREATITIS. Lancet. 1963 Aug 24;2(7304):384–384. doi: 10.1016/s0140-6736(63)93061-7. [DOI] [PubMed] [Google Scholar]
  177. Walker L. G., Jr, Stone H. H., Apple D. G. Pseudocysts of the pancreas: a review of 59 cases. South Med J. 1967 Apr;60(4):389–393. doi: 10.1097/00007611-196704000-00013. [DOI] [PubMed] [Google Scholar]
  178. Wanger F. Die diagnostische und therapeutischen Bedeutung von Blutgerinnungsstörungen bei der akuten Pancreatitis. Helv Chir Acta. 1966 Jan;33(1):118–127. [PubMed] [Google Scholar]
  179. Weiner S., Gramatica L., Voegle L. D., Hauman R. L., Anderson M. C. Role of the lymphatic system in the pathogenesis of inflammatory disease in the biliary tract and pancreas. Am J Surg. 1970 Jan;119(1):55–61. doi: 10.1016/0002-9610(70)90011-5. [DOI] [PubMed] [Google Scholar]
  180. White M. T., Morgan A., Hopton D. Postoperative pancreatitis. A study of seventy cases. Am J Surg. 1970 Aug;120(2):132–137. doi: 10.1016/s0002-9610(70)80100-3. [DOI] [PubMed] [Google Scholar]
  181. Whitten D. M., Feingold M., Eisenklam E. J. Hereditary pancreatitis. Am J Dis Child. 1968 Oct;116(4):426–428. doi: 10.1001/archpedi.1968.02100020430016. [DOI] [PubMed] [Google Scholar]
  182. Wislocki L. C. Acute pancreatitis in infectious mononucleosis. N Engl J Med. 1966 Aug 11;275(6):322–323. doi: 10.1056/NEJM196608112750609. [DOI] [PubMed] [Google Scholar]
  183. Witte C. L., Schanzer B. Pancreatitis due to mumps. JAMA. 1968 Mar 18;203(12):1068–1069. [PubMed] [Google Scholar]
  184. Wool G., Goldring D. Pseudocyst of the pancreas. Report of five cases and review of literature. J Pediatr. 1967 Apr;70(4):586–594. doi: 10.1016/s0022-3476(67)80043-x. [DOI] [PubMed] [Google Scholar]
  185. Wright P. W., Goodhead B. Prevention of hemorrhagic pancreatitis with fibrinolysin or heparin. Arch Surg. 1970 Jan;100(1):42–46. doi: 10.1001/archsurg.1970.01340190044010. [DOI] [PubMed] [Google Scholar]
  186. Wright P. W., Goodhead B. The value of dextrans in the treatment of experimental pancreatitis. Surgery. 1970 May;67(5):807–815. [PubMed] [Google Scholar]
  187. YIN E. T. KINETICS OF HUMAN BLOOD COAGULATION INDUCED BY TRYPSIN. Thromb Diath Haemorrh. 1964 Oct 15;12:307–330. [PubMed] [Google Scholar]
  188. Zeller M., Hetz H. H. Rupture of a pancreatic cyst into the portal vein. Report of a case of subcutaneous nodular and generalized fat necrosis. JAMA. 1966 Mar 7;195(10):869–871. doi: 10.1001/jama.1966.03100100121045. [DOI] [PubMed] [Google Scholar]
  189. Zieve L. Relationship between acute pancreatitis and hyperlipemia. Med Clin North Am. 1968 Nov;52(6):1493–1501. [PubMed] [Google Scholar]
  190. Zimberg Y. H. Pancreatitis: principles of management. Surg Clin North Am. 1968 Aug;48(4):889–905. doi: 10.1016/s0039-6109(16)38590-5. [DOI] [PubMed] [Google Scholar]
  191. Zimmerman M. J., Dreiling D. A., Rosenberg I. R., Janowitz H. D. Secretion of calcium by the canine pancreas. Gastroenterology. 1967 May;52(5):865–870. [PubMed] [Google Scholar]

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