Skip to main content
Environmental Health Perspectives logoLink to Environmental Health Perspectives
. 1995 Mar;103(Suppl 2):97–102. doi: 10.1289/ehp.95103s297

Relationship between summertime ambient ozone levels and emergency department visits for asthma in central New Jersey.

C P Weisel 1, R P Cody 1, P J Lioy 1
PMCID: PMC1518842  PMID: 7614954

Abstract

The 5-year retrospective study of the association between temperature and emergency department (ED) visits for asthma with mean ambient ozone levels between 10:00 and 15:00 was conducted in central New Jersey during the summer months. An association was identified in each of the years (1986-1990). Between 8 and 34% of the total variance in ED visits for asthma was explained by the two environmental variables in the step-wise multiple regression analysis. ED visits occurred 28% more frequently when the mean ozone levels were > 0.06 ppm than when they were < 0.06 ppm. This result was statistically significant in a covariance analysis. An evaluation of the effects of ozone on asthmatics reported in the literature was completed to determine if, as proposed by Bates, the results from different types of studies were coherent among the health metrics. A consistency in the magnitude of reported effects and the time lag between exposure and response for four different health indices (symptom reports, decrements in expiratory flow, ED visits, and hospital admissions) was identified and indicates a coherence between ozone and respiratory response to ozone exposure. This supports a proposition that ozone adversely affects asthmatics at levels below the current U.S. standard.

Full text

PDF
97

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abbey D. E., Mills P. K., Petersen F. F., Beeson W. L. Long-term ambient concentrations of total suspended particulates and oxidants as related to incidence of chronic disease in California Seventh-Day Adventists. Environ Health Perspect. 1991 Aug;94:43–50. doi: 10.1289/ehp.94-1567944. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Abbey D. E., Petersen F., Mills P. K., Beeson W. L. Long-term ambient concentrations of total suspended particulates, ozone, and sulfur dioxide and respiratory symptoms in a nonsmoking population. Arch Environ Health. 1993 Jan-Feb;48(1):33–46. doi: 10.1080/00039896.1993.9938391. [DOI] [PubMed] [Google Scholar]
  3. Bates D. V., Baker-Anderson M., Sizto R. Asthma attack periodicity: a study of hospital emergency visits in Vancouver. Environ Res. 1990 Feb;51(1):51–70. doi: 10.1016/s0013-9351(05)80182-3. [DOI] [PubMed] [Google Scholar]
  4. Bates D. V. Health indices of the adverse effects of air pollution: the question of coherence. Environ Res. 1992 Dec;59(2):336–349. doi: 10.1016/s0013-9351(05)80040-4. [DOI] [PubMed] [Google Scholar]
  5. Bates D. V., Sizto R. Air pollution and hospital admissions in Southern Ontario: the acid summer haze effect. Environ Res. 1987 Aug;43(2):317–331. doi: 10.1016/s0013-9351(87)80032-4. [DOI] [PubMed] [Google Scholar]
  6. Bates D. V., Sizto R. The Ontario Air Pollution Study: identification of the causative agent. Environ Health Perspect. 1989 Feb;79:69–72. doi: 10.1289/ehp.897969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Berry M., Lioy P. J., Gelperin K., Buckler G., Klotz J. Accumulated exposure to ozone and measurement of health effects in children and counselors at two summer camps. Environ Res. 1991 Apr;54(2):135–150. doi: 10.1016/s0013-9351(05)80096-9. [DOI] [PubMed] [Google Scholar]
  8. Cody R. P., Weisel C. P., Birnbaum G., Lioy P. J. The effect of ozone associated with summertime photochemical smog on the frequency of asthma visits to hospital emergency departments. Environ Res. 1992 Aug;58(2):184–194. doi: 10.1016/s0013-9351(05)80214-2. [DOI] [PubMed] [Google Scholar]
  9. Folinsbee L. J., McDonnell W. F., Horstman D. H. Pulmonary function and symptom responses after 6.6-hour exposure to 0.12 ppm ozone with moderate exercise. JAPCA. 1988 Jan;38(1):28–35. doi: 10.1080/08940630.1988.10466349. [DOI] [PubMed] [Google Scholar]
  10. Horstman D. H., Folinsbee L. J., Ives P. J., Abdul-Salaam S., McDonnell W. F. Ozone concentration and pulmonary response relationships for 6.6-hour exposures with five hours of moderate exercise to 0.08, 0.10, and 0.12 ppm. Am Rev Respir Dis. 1990 Nov;142(5):1158–1163. doi: 10.1164/ajrccm/142.5.1158. [DOI] [PubMed] [Google Scholar]
  11. Khan A. U. The role of air pollution and weather changes in childhood asthma. Ann Allergy. 1977 Dec;39(6):397–400. [PubMed] [Google Scholar]
  12. Koenig J. Q., Covert D. S., Smith M. S., van Belle G., Pierson W. E. The pulmonary effects of ozone and nitrogen dioxide alone and combined in healthy and asthmatic adolescent subjects. Toxicol Ind Health. 1988 Dec;4(4):521–532. doi: 10.1177/074823378800400410. [DOI] [PubMed] [Google Scholar]
  13. Krzyzanowski M., Quackenboss J. J., Lebowitz M. D. Relation of peak expiratory flow rates and symptoms to ambient ozone. Arch Environ Health. 1992 Mar-Apr;47(2):107–115. doi: 10.1080/00039896.1992.10118763. [DOI] [PubMed] [Google Scholar]
  14. Kurata J. H., Glovsky M. M., Newcomb R. L., Easton J. G. A multifactorial study of patients with asthma. Part 2: air pollution, animal dander and asthma symptoms. Ann Allergy. 1976 Dec;37(6):398–409. [PubMed] [Google Scholar]
  15. Larsen R. I., McDonnell W. F., Horstman D. H., Folinsbee L. J. An air quality data analysis system for interrelating effects, standards, and needed source reductions: Part 11. A lognormal model relating human lung function decrease to O3 exposure. J Air Waste Manage Assoc. 1991 Apr;41(4):455–459. doi: 10.1080/10473289.1991.10466858. [DOI] [PubMed] [Google Scholar]
  16. Lebowitz M. D., Collins L., Holberg C. J. Time series analyses of respiratory responses to indoor and outdoor environmental phenomena. Environ Res. 1987 Aug;43(2):332–341. doi: 10.1016/s0013-9351(87)80033-6. [DOI] [PubMed] [Google Scholar]
  17. Lippmann M. Health effects of tropospheric ozone: review of recent research findings and their implications to ambient air quality standards. J Expo Anal Environ Epidemiol. 1993 Jan-Mar;3(1):103–129. [PubMed] [Google Scholar]
  18. Molfino N. A., Wright S. C., Katz I., Tarlo S., Silverman F., McClean P. A., Szalai J. P., Raizenne M., Slutsky A. S., Zamel N. Effect of low concentrations of ozone on inhaled allergen responses in asthmatic subjects. Lancet. 1991 Jul 27;338(8761):199–203. doi: 10.1016/0140-6736(91)90346-q. [DOI] [PubMed] [Google Scholar]
  19. Pönkä A. Asthma and low level air pollution in Helsinki. Arch Environ Health. 1991 Sep-Oct;46(5):262–270. doi: 10.1080/00039896.1991.9934386. [DOI] [PubMed] [Google Scholar]
  20. Rennick G. J., Jarman F. C. Are children with asthma affected by smog? Med J Aust. 1992 Jun 15;156(12):837–841. doi: 10.5694/j.1326-5377.1992.tb136995.x. [DOI] [PubMed] [Google Scholar]
  21. Richards W., Azen S. P., Weiss J., Stocking S., Church J. Los Angeles air pollution and asthma in children. Ann Allergy. 1981 Nov;47(5 Pt 1):348–354. [PubMed] [Google Scholar]
  22. Schmitzberger R., Rhomberg K., Büchele H., Puchegger R., Schmitzberger-Natzmer D., Kemmler G., Panosch B. Effects of air pollution on the respiratory tract of children. Pediatr Pulmonol. 1993 Feb;15(2):68–74. doi: 10.1002/ppul.1950150203. [DOI] [PubMed] [Google Scholar]
  23. Schwartz J. Air pollution and the duration of acute respiratory symptoms. Arch Environ Health. 1992 Mar-Apr;47(2):116–122. doi: 10.1080/00039896.1992.10118764. [DOI] [PubMed] [Google Scholar]
  24. Spektor D. M., Lippmann M., Thurston G. D., Lioy P. J., Stecko J., O'Connor G., Garshick E., Speizer F. E., Hayes C. Effects of ambient ozone on respiratory function in healthy adults exercising outdoors. Am Rev Respir Dis. 1988 Oct;138(4):821–828. doi: 10.1164/ajrccm/138.4.821. [DOI] [PubMed] [Google Scholar]
  25. Thurston G. D., Ito K., Kinney P. L., Lippmann M. A multi-year study of air pollution and respiratory hospital admissions in three New York State metropolitan areas: results for 1988 and 1989 summers. J Expo Anal Environ Epidemiol. 1992 Oct-Dec;2(4):429–450. [PubMed] [Google Scholar]
  26. Wardlaw A. J. The role of air pollution in asthma. Clin Exp Allergy. 1993 Feb;23(2):81–96. doi: 10.1111/j.1365-2222.1993.tb00303.x. [DOI] [PubMed] [Google Scholar]
  27. White M. C., Etzel R. A., Wilcox W. D., Lloyd C. Exacerbations of childhood asthma and ozone pollution in Atlanta. Environ Res. 1994 Apr;65(1):56–68. doi: 10.1006/enrs.1994.1021. [DOI] [PubMed] [Google Scholar]
  28. Whittemore A. S., Korn E. L. Asthma and air pollution in the Los Angeles area. Am J Public Health. 1980 Jul;70(7):687–696. doi: 10.2105/ajph.70.7.687. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Environmental Health Perspectives are provided here courtesy of National Institute of Environmental Health Sciences

RESOURCES