Abstract
In Erfurt, Germany, unfavorable geography and emissions from coal burning lead to very high ambient pollution (up to about 4000 micrograms/m3 SO2 in 1980-89). To assess possible health effects of these exposures, total daily mortality was obtained for this same period. A multivariate model was fitted, including corrections for long-term fluctuations, influenza epidemics, and meterology, before analyzing the effect of pollution. The best fit for pollution was obtained for log (SO2 daily mean) with a lag of 2 days. Daily mortality increased by 10% for an increase in SO2 from 23 to 929 micrograms/m3 (5% quantile to 95% quantile). A harvesting effect (fewer people die on a given day if more deaths occurred in the last 15 days) may modify this by +/- 2%. The effect for particulates (SP, 1988-89 only) was stronger than the effect of SO2. Log SP (daily mean) increasing from 15 micrograms/m3 to 331 micrograms/m3 (5% quantile to 95% quantile) was associated with a 22% increase in mortality. Depending on harvesting, the observable effect may lie between 14% and 27%. There is no indication of a threshold or synergism. The effects of air pollution are smaller than the effects of influenza epidemics and are of the same size as meterologic effects. The results for the lower end of the dose range are in agreement with linear models fitted in studies of moderate air pollution and episode studies.
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- Buechley R. W., Riggan W. B., Hasselblad V., VanBruggen J. B. SO2 levels and perturbations in mortality. A study in the New York-New Jersey metropolis. Arch Environ Health. 1973 Sep;27(3):134–137. doi: 10.1080/00039896.1973.10666341. [DOI] [PubMed] [Google Scholar]
- Hatzakis A., Katsouyanni K., Kalandidi A., Day N., Trichopoulos D. Short-term effects of air pollution on mortality in Athens. Int J Epidemiol. 1986 Mar;15(1):73–81. doi: 10.1093/ije/15.1.73. [DOI] [PubMed] [Google Scholar]
- Hecker H., Basler H. D., Wolf E. Schwankungen der Mortalität in Beziehung zur Luftverschmutzung. Methods Inf Med. 1975 Oct;14(4):218–223. [PubMed] [Google Scholar]
- Holland W. W., Bennett A. E., Cameron I. R., Florey C. V., Leeder S. R., Schilling R. S., Swan A. V., Waller R. E. Health effects of particulate pollution: reappraising the evidence. Am J Epidemiol. 1979 Nov;110(5):527–659. doi: 10.1093/oxfordjournals.aje.a112836. [DOI] [PubMed] [Google Scholar]
- Höpken W., Willers H. Epidemiologie der Influenza seit 1968. Internist (Berl) 1985 Feb;26(2):83–88. [PubMed] [Google Scholar]
- Lautenschläger D., Dörre W. H., Horn K., Kowalewicz B. Mortalitätsuntersuchung im Zusammenhang mit lufthygienisch bedenklichen Situationen. Z Gesamte Hyg. 1991 Mar;37(3):127–128. [PubMed] [Google Scholar]
- Mazumdar S., Schimmel H., Higgins I. T. Relation of daily mortality to air pollution: an analysis of 14 London winters, 1958/59-1971/72. Arch Environ Health. 1982 Jul-Aug;37(4):213–220. doi: 10.1080/00039896.1982.10667567. [DOI] [PubMed] [Google Scholar]
- Mazumdar S., Sussman N. Relationships of air pollution to health: results from the Pittsburgh study. Arch Environ Health. 1983 Jan-Feb;38(1):17–24. doi: 10.1080/00039896.1983.10543974. [DOI] [PubMed] [Google Scholar]
- Ostro B. A search for a threshold in the relationship of air pollution to mortality: a reanalysis of data on London winters. Environ Health Perspect. 1984 Dec;58:397–399. doi: 10.1289/ehp.8458397. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schimmel H., Greenburg L. A study of the relation of pollution to mortality New York City, 1963-1968. J Air Pollut Control Assoc. 1972 Aug;22(8):607–616. doi: 10.1080/00022470.1972.10469688. [DOI] [PubMed] [Google Scholar]
- Schimmel H., Murawski T. J. Proceedings: The relation of air pollution to mortality. J Occup Med. 1976 May;18(5):316–333. doi: 10.1097/00043764-197605000-00006. [DOI] [PubMed] [Google Scholar]
- Schmitt O. A. Smogepisoden im Ruhrgebiet seit 1980. Schriftenr Ver Wasser Boden Lufthyg. 1986;69:119–127. [PubMed] [Google Scholar]
- Schwartz J., Dockery D. W. Increased mortality in Philadelphia associated with daily air pollution concentrations. Am Rev Respir Dis. 1992 Mar;145(3):600–604. doi: 10.1164/ajrccm/145.3.600. [DOI] [PubMed] [Google Scholar]
- Schwartz J., Marcus A. Mortality and air pollution in London: a time series analysis. Am J Epidemiol. 1990 Jan;131(1):185–194. doi: 10.1093/oxfordjournals.aje.a115473. [DOI] [PubMed] [Google Scholar]
- Schwartz J. Particulate air pollution and daily mortality in Detroit. Environ Res. 1991 Dec;56(2):204–213. doi: 10.1016/s0013-9351(05)80009-x. [DOI] [PubMed] [Google Scholar]
- Steiger H., Brockhaus A. Untersuchungen über den Zusammenhang zwischen Luftverunreinigungen und Mortalität im Ruhrgebiet. Naturwissenschaften. 1966 Oct;53(19):498–498. doi: 10.1007/BF00622983. [DOI] [PubMed] [Google Scholar]
- Steiger H. Mortalitätsuntersuchung während der Smogwetterlage im westlichen Ruhrgebiet am 17. Januar 1979. Zentralbl Bakteriol Mikrobiol Hyg B. 1980 Sep;171(4-5):445–447. [PubMed] [Google Scholar]
- Ware J. H., Thibodeau L. A., Speizer F. E., Colome S., Ferris B. G., Jr Assessment of the health effects of atmospheric sulfur oxides and particulate matter: evidence from observational studies. Environ Health Perspect. 1981 Oct;41:255–276. doi: 10.1289/ehp.8141255. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wichmann H. E., Brockhaus A., Schlipköter H. W. Smogepisoden in Nordrhein-Westfalen und ihre gesundheitlichen Auswirkungen. Offentl Gesundheitswes. 1988 Jun;50(6):314–318. [PubMed] [Google Scholar]
- Wichmann H. E., Mueller W., Allhoff P., Beckmann M., Bocter N., Csicsaky M. J., Jung M., Molik B., Schoeneberg G. Health effects during a smog episode in West Germany in 1985. Environ Health Perspect. 1989 Feb;79:89–99. doi: 10.1289/ehp.897989. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wichmann H. E., Spix C. Ergänzende Betrachtungen zu den gesundheitlichen Auswirkungen der Smogepisode 1985. Offentl Gesundheitswes. 1990 Jun;52(6):260–266. [PubMed] [Google Scholar]
- Wichmann H. E., Sugiri D., Herold G., Knülle E. Atemwiderstandsmessungen bei Gesunden im Winterhalbjahr 1985/86 und im Januar/Februar 1987. Zentralbl Bakteriol Mikrobiol Hyg B. 1988 Jan;185(4-5):509–519. [PubMed] [Google Scholar]