Abstract
Sulfonamides can be used in the treatment of impetigo with vastly increased safety and with more effectiveness in powder rather than ointment form when combined with urea powder in a ratio of approximately three parts of sulfonamide to one of urea.
Of 701 patients treated with such a mixture, 95.6 per cent were cured within a week. The only complication was local dermatitis which occurred in 0.57 per cent of patients. This compares favorably with results obtained with newer and expensive drugs which usually have the disadvantage of being used in a greasy vehicle.
The low incidence of sensitivity reaction to the sulfonamide-urea powder is perhaps ascribable in part to the avoidance of a greasy vehicle.
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Selected References
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