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. 1953 Nov;79(5):381–385.

MULTIPLE SCLEROSIS—Its Frequency and Distribution, with Special Reference to San Francisco

Leonard T Kurland, Henry W Newman
PMCID: PMC1521900  PMID: 13106716

Abstract

Epidemiologic surveys of multiple sclerosis were conducted in 1949 in San Francisco, Winnipeg, Boston, New Orleans, and Denver. Reports of cases for 1939 through 1948 were obtained from record offices, hospitals and clinics, and private physicians. The basis for the observations was the group of “probable” cases among residents.

In San Francisco these probable cases in residents numbered 415; however, in only 146 of these was the onset between 1939 and 1948. Of the 143 patients who were white, 51 were male and 92 female. The average annual incidence based on these figures was 2.1 per 100,000—1.5 for males and 2.6 for females.

Prevalence, based on probable cases in residents on January 1, 1949, was 29.7 cases per 100,000 population—21.2 for males and 38.1 for females.

Mortality was 0.7 per 100,000 population—0.9 for females and 0.6 for males.

In comparison of the findings for San Francisco with those of other cities, both the incidence and the severity of the disease appear to decrease from north to south.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. KURLAND L. T., DODGE H. J. Multiple sclerosis; its frequency and distribution, with special reference to Denver, Colorado. Neurology. 1953 Aug;3(8):577–585. doi: 10.1212/wnl.3.8.577. [DOI] [PubMed] [Google Scholar]
  2. KURLAND L. T. The frequency and geographic distribution of multiple sclerosis as indicated by mortality statistics and morbidity surveys in the United States and Canada. Am J Hyg. 1952 May;55(3):457–481. doi: 10.1093/oxfordjournals.aje.a119535. [DOI] [PubMed] [Google Scholar]
  3. LIMBURG C. C. The geographic distribution of multiple sclerosis and its estimated prevalence in the United States. Res Publ Assoc Res Nerv Ment Dis. 1950;28:15–24. [PubMed] [Google Scholar]
  4. WESTLUND K. B., KURLAND L. T. Studies on multiple sclerosis in Winnipeg, Manitoba, and New Orleans, Louisiana. II. A controlled investigation of factors in the life history of the Winnipeg patients. Am J Hyg. 1953 May;57(3):397–407. doi: 10.1093/oxfordjournals.aje.a119583. [DOI] [PubMed] [Google Scholar]

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