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. 1998 Feb;106(Suppl 1):379–381. doi: 10.1289/ehp.98106s1379

Biological effects of low-level exposures: a perspective from U.S. EPA scientists.

J M Davis 1, W H Farland 1
PMCID: PMC1533293  PMID: 9539033

Abstract

Biological effects of low-level exposures (BELLE) may be very important in characterizing the potential health risks of environmental pollutants. Before some features of BELLE, such as effects that may be modulated by adaptive or defense mechanisms, can be taken into greater consideration in U.S. Environmental Protection Agency risk assessments, however adequate information on a toxicant's mode of action and answers to other questions are needed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Calabrese E. J. Expanding the reference dose concept to incorporate and optimize beneficial effects while preventing toxic responses from nonessential toxicants. Regul Toxicol Pharmacol. 1996 Aug;24(1 Pt 2):S68–S75. doi: 10.1006/rtph.1996.0080. [DOI] [PubMed] [Google Scholar]

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