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. 1995 Mar;99(3):313–315. doi: 10.1111/j.1365-2249.1995.tb05551.x

The molecular basis for a polyspecific antibody.

M G Wing
PMCID: PMC1534201  PMID: 7882551

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Avrameas S., Guilbert B., Mahana W., Matsiota P., Ternynck T. Recognition of self and non-self constituents by polyspecific autoreceptors. Int Rev Immunol. 1988 Mar;3(1-2):1–15. doi: 10.3109/08830188809051179. [DOI] [PubMed] [Google Scholar]
  2. Baccala R., Quang T. V., Gilbert M., Ternynck T., Avrameas S. Two murine natural polyreactive autoantibodies are encoded by nonmutated germ-line genes. Proc Natl Acad Sci U S A. 1989 Jun;86(12):4624–4628. doi: 10.1073/pnas.86.12.4624. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bohn J., Niemann B., Roggenbuck D., Döcke W., Jahn S. Tumour cell binding by a human monoclonal IgM antibody from the spleen of a non-tumour-associated patient is due to somatic mutations in the VH gene. Clin Exp Immunol. 1995 Mar;99(3):376–383. doi: 10.1111/j.1365-2249.1995.tb05561.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Casali P., Notkins A. L. Probing the human B-cell repertoire with EBV: polyreactive antibodies and CD5+ B lymphocytes. Annu Rev Immunol. 1989;7:513–535. doi: 10.1146/annurev.iy.07.040189.002501. [DOI] [PubMed] [Google Scholar]
  5. Casali P., Prabhakar B. S., Notkins A. L. Characterization of multireactive autoantibodies and identification of Leu-1+ B lymphocytes as cells making antibodies binding multiple self and exogenous molecules. Int Rev Immunol. 1988 Mar;3(1-2):17–45. doi: 10.3109/08830188809051180. [DOI] [PubMed] [Google Scholar]
  6. Chow D. A., Bennet R. D. Low natural antibody and low in vivo tumor resistance, in xid-bearing B-cell deficient mice. J Immunol. 1989 May 15;142(10):3702–3706. [PubMed] [Google Scholar]
  7. Colman P. M. Structure of antibody-antigen complexes: implications for immune recognition. Adv Immunol. 1988;43:99–132. doi: 10.1016/s0065-2776(08)60364-8. [DOI] [PubMed] [Google Scholar]
  8. Dighiero G., Lymberi P., Mazié J. C., Rouyre S., Butler-Browne G. S., Whalen R. G., Avrameas S. Murine hybridomas secreting natural monoclonal antibodies reacting with self antigens. J Immunol. 1983 Nov;131(5):2267–2272. [PubMed] [Google Scholar]
  9. Guilbert B., Dighiero G., Avrameas S. Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization. J Immunol. 1982 Jun;128(6):2779–2787. [PubMed] [Google Scholar]
  10. Harindranath N., Donadel G., Sigounas G., Notkins A. L. Comparison of complete nucleotide sequence of the human IgM heavy chain constant region of polyreactive and monoreactive antibodies. Mol Immunol. 1993 Jan;30(1):111–112. doi: 10.1016/0161-5890(93)90434-d. [DOI] [PubMed] [Google Scholar]
  11. Ikematsu H., Kasaian M. T., Schettino E. W., Casali P. Structural analysis of the VH-D-JH segments of human polyreactive IgG mAb. Evidence for somatic selection. J Immunol. 1993 Oct 1;151(7):3604–3616. [PMC free article] [PubMed] [Google Scholar]
  12. Kasaian M. T., Casali P. Autoimmunity-prone B-1 (CD5 B) cells, natural antibodies and self recognition. Autoimmunity. 1993;15(4):315–329. doi: 10.3109/08916939309115755. [DOI] [PubMed] [Google Scholar]
  13. McClarin J. A., Frederick C. A., Wang B. C., Greene P., Boyer H. W., Grable J., Rosenberg J. M. Structure of the DNA-Eco RI endonuclease recognition complex at 3 A resolution. Science. 1986 Dec 19;234(4783):1526–1541. doi: 10.1126/science.3024321. [DOI] [PubMed] [Google Scholar]
  14. Poncet P., Matthes T., Billecocq A., Dighiero G. Immunochemical studies of polyspecific natural autoantibodies: charge, lipid reactivity, Fab'2 fragments activity and complement fixation. Mol Immunol. 1988 Oct;25(10):981–989. doi: 10.1016/0161-5890(88)90004-1. [DOI] [PubMed] [Google Scholar]
  15. Riechmann L., Clark M., Waldmann H., Winter G. Reshaping human antibodies for therapy. Nature. 1988 Mar 24;332(6162):323–327. doi: 10.1038/332323a0. [DOI] [PubMed] [Google Scholar]
  16. Roggenbuck D., König H., Niemann B., Schoenherr G., Jahn S., Porstmann T. Real-time biospecific interaction analysis of a natural human polyreactive monoclonal IgM antibody and its Fab and scFv fragments with several antigens. Scand J Immunol. 1994 Jul;40(1):64–70. doi: 10.1111/j.1365-3083.1994.tb03434.x. [DOI] [PubMed] [Google Scholar]
  17. Rosenstein R. W., Musson R. A., Armstrong M. K., Konigsberg W. H., Richards F. F. Contact regions for dinitrophenyl and menadione haptens in an immunoglobulin binding more than one antigen. Proc Natl Acad Sci U S A. 1972 Apr;69(4):877–881. doi: 10.1073/pnas.69.4.877. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Seeman N. C., Rosenberg J. M., Rich A. Sequence-specific recognition of double helical nucleic acids by proteins. Proc Natl Acad Sci U S A. 1976 Mar;73(3):804–808. doi: 10.1073/pnas.73.3.804. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Shlomchik M., Mascelli M., Shan H., Radic M. Z., Pisetsky D., Marshak-Rothstein A., Weigert M. Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J Exp Med. 1990 Jan 1;171(1):265–292. doi: 10.1084/jem.171.1.265. [DOI] [PMC free article] [PubMed] [Google Scholar]

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