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. 1994 Jan;95(1):1–2. doi: 10.1111/j.1365-2249.1994.tb06005.x

Germ-line transcripts and class switching.

J Farrant
PMCID: PMC1534646  PMID: 8287591

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Berton M. T., Uhr J. W., Vitetta E. S. Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma. Proc Natl Acad Sci U S A. 1989 Apr;86(8):2829–2833. doi: 10.1073/pnas.86.8.2829. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Berton M. T., Vitetta E. S. IL-4-induced expression of germline gamma 1 transcripts in B cells following cognate interactions with T helper cells. Int Immunol. 1992 Mar;4(3):387–396. doi: 10.1093/intimm/4.3.387. [DOI] [PubMed] [Google Scholar]
  3. Berton M. T., Vitetta E. S. Interleukin 4 induces changes in the chromatin structure of the gamma 1 switch region in resting B cells before switch recombination. J Exp Med. 1990 Jul 1;172(1):375–378. doi: 10.1084/jem.172.1.375. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Chen J., Alt F. W. Gene rearrangement and B-cell development. Curr Opin Immunol. 1993 Apr;5(2):194–200. doi: 10.1016/0952-7915(93)90004-c. [DOI] [PubMed] [Google Scholar]
  5. Gauchat J. F., Aversa G., Gascan H., de Vries J. E. Modulation of IL-4 induced germline epsilon RNA synthesis in human B cells by tumor necrosis factor-alpha, anti-CD40 monoclonal antibodies or transforming growth factor-beta correlates with levels of IgE production. Int Immunol. 1992 Mar;4(3):397–406. doi: 10.1093/intimm/4.3.397. [DOI] [PubMed] [Google Scholar]
  6. Harriman W., Völk H., Defranoux N., Wabl M. Immunoglobulin class switch recombination. Annu Rev Immunol. 1993;11:361–384. doi: 10.1146/annurev.iy.11.040193.002045. [DOI] [PubMed] [Google Scholar]
  7. Ichiki T., Takahashi W., Watanabe T. Regulation of the expression of human C epsilon germline transcript. Identification of a novel IL-4 responsive element. J Immunol. 1993 Jun 15;150(12):5408–5417. [PubMed] [Google Scholar]
  8. Islam K. B., Baskin B., Christensson B., Hammarström L., Smith C. I. In vivo expression of human immunoglobulin germ-line mRNA in normal and in immunodeficient individuals. Clin Exp Immunol. 1994 Jan;95(1):3–9. doi: 10.1111/j.1365-2249.1994.tb06006.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Jung S., Rajewsky K., Radbruch A. Shutdown of class switch recombination by deletion of a switch region control element. Science. 1993 Feb 12;259(5097):984–987. doi: 10.1126/science.8438159. [DOI] [PubMed] [Google Scholar]
  10. Kerr L. D., Miller D. B., Matrisian L. M. TGF-beta 1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence. Cell. 1990 Apr 20;61(2):267–278. doi: 10.1016/0092-8674(90)90807-q. [DOI] [PubMed] [Google Scholar]
  11. Rothman P., Chen Y. Y., Lutzker S., Li S. C., Stewart V., Coffman R., Alt F. W. Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C epsilon. Mol Cell Biol. 1990 Apr;10(4):1672–1679. doi: 10.1128/mcb.10.4.1672. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Rothman P., Li S. C., Alt F. W. The molecular events in heavy chain class-switching. Semin Immunol. 1989 Sep;1(1):65–77. [PubMed] [Google Scholar]
  13. Rothman P., Lutzker S., Gorham B., Stewart V., Coffman R., Alt F. W. Structure and expression of germline immunoglobulin gamma 3 heavy chain gene transcripts: implications for mitogen and lymphokine directed class-switching. Int Immunol. 1990;2(7):621–627. doi: 10.1093/intimm/2.7.621. [DOI] [PubMed] [Google Scholar]
  14. Schultz C. L., Rothman P., Kühn R., Kehry M., Müller W., Rajewsky K., Alt F., Coffman R. L. T helper cell membranes promote IL-4-independent expression of germ-line C gamma 1 transcripts in B cells. J Immunol. 1992 Jul 1;149(1):60–64. [PubMed] [Google Scholar]
  15. Wakatsuki Y., Strober W. Effect of downregulation of germline transcripts on immunoglobulin A isotype differentiation. J Exp Med. 1993 Jul 1;178(1):129–138. doi: 10.1084/jem.178.1.129. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Xu L., Gorham B., Li S. C., Bottaro A., Alt F. W., Rothman P. Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching. Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3705–3709. doi: 10.1073/pnas.90.8.3705. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Xu M. Z., Stavnezer J. Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer. EMBO J. 1992 Jan;11(1):145–155. doi: 10.1002/j.1460-2075.1992.tb05037.x. [DOI] [PMC free article] [PubMed] [Google Scholar]

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