Abstract
Immunoglobulin levels were measured in serum samples from 36 patients with different clinical forms of chronic Chagas' disease. Increased IgA levels were observed in 50% of the patients in the chronic digestive group and there was a significant correlation with the severity of the disease. IgG and IgM levels were within the normal range. Anti-ssDNA antibodies and EVI (endothelium, vessels and interstitium) antibodies were found in some patients with different clinical forms of the disease.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brener Z. Immunity to Trypanosoma cruzi. Adv Parasitol. 1980;18:247–292. doi: 10.1016/s0065-308x(08)60401-7. [DOI] [PubMed] [Google Scholar]
- Camargo M. E., Hoshino S., Siqueira G. R. Hemagglutination with preserved, sensitized cells, a practical test for routine serologic diagnosis of American trypanosomiasis. Rev Inst Med Trop Sao Paulo. 1973 Mar-Apr;15(2):81–85. [PubMed] [Google Scholar]
- Cossio P. M., Diez C., Szarfman A., Kreutzer E., Candiolo B., Arana R. M. Chagasic cardiopathy. Demonstration of a serum gamma globulin factor which reacts with endocardium and vascular structures. Circulation. 1974 Jan;49(1):13–21. doi: 10.1161/01.cir.49.1.13. [DOI] [PubMed] [Google Scholar]
- De Freitas G., Da Costa S. C., Pereira N. de M., Quintão L. G., De Souza J. G. Imunoglobulinas na fase crônica da doença de Chagas. Mem Inst Oswaldo Cruz. 1976;74(2):183–190. doi: 10.1590/s0074-02761976000200005. [DOI] [PubMed] [Google Scholar]
- Hoshino-Shimizu S., Camargo M. E., Nagasse T. K. A stable polysaccharide-hemagglutination reagent for the diagnosis of acute or recent Trypanosoma cruzi infections. Rev Inst Med Trop Sao Paulo. 1978 Jul-Aug;20(4):208–212. [PubMed] [Google Scholar]
- Lelchuk R., Dalmasso A. P., Inglesini C. L., Alvarez M., Cerisola J. A. Immunoglobulin studies in serum of patients with American trypanosomiasis (Chagas' disease). Clin Exp Immunol. 1970 Apr;6(4):547–555. [PMC free article] [PubMed] [Google Scholar]
- Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
- Marsden P. D., Seah S. K., Mott K. E., Prata A., Platt H. Immunoglobulins in Chagas' disease. J Trop Med Hyg. 1970 Jul;73(7):157–161. [PubMed] [Google Scholar]
- NUSSENZVEIG V., SONNTAG R. Xenodiagnóstico artificial; novo processo; primeiros resultados positivos. Rev Paul Med. 1952 Jan;40(1):41–43. [PubMed] [Google Scholar]
- Thomasi T. B., Jr Secretory immunoglobulins. N Engl J Med. 1972 Sep 7;287(10):500–506. doi: 10.1056/NEJM197209072871008. [DOI] [PubMed] [Google Scholar]
- Vattuone N. H., Szarfman A., Gonzalez Cappa S. M. Antibody response and immunoglobulin levels in humans with acute or chronic Trypanosoma cruzi infections (Chagas' disease). J Trop Med Hyg. 1973 Feb;76(2):45–47. [PubMed] [Google Scholar]
- Waldman R. H., Mach J. P., Stella M. M., Rowe D. S. Secretory IgA in human serum. J Immunol. 1970 Jul;105(1):43–47. [PubMed] [Google Scholar]
- Walker W. A., Isselbacher K. J. Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders. Gastroenterology. 1974 Sep;67(3):531–550. [PubMed] [Google Scholar]
- de REZENDE J., LAUAR K. M., de OLIVEIRA A. [Clinical and radiological aspects of aperistalsis of the esophagus]. Rev Bras Gastroenterol. 1960 Sep-Dec;12:247–262. [PubMed] [Google Scholar]