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. 1984 Mar;55(3):629–635.

Thymic hormone containing cells. IV. Fluctuations in the thyroid hormone levels in vivo can modulate the secretion of thymulin by the epithelial cells of young mouse thymus.

W Savino, B Wolf, S Aratan-Spire, M Dardenne
PMCID: PMC1535945  PMID: 6584256

Abstract

The influence of thyroid status on serum level and thymic content of thymulin, a thymic hormone, has been studied in young rats and mice treated by tri-iodothyronine (T3) or 6N-propyl-2-thiouracil (PTU). We showed that in vivo T3 administration induces in young animals an increase of their thymulin serum levels and of the number of thymulin containing cells in their thymuses. Conversely, a treatment with PTU decreases the thymulin serum levels and the number of cells containing the hormone. These findings suggest that thyroid hormones stimulate the synthesis and secretion of thymulin and represent further evidence for the hormonal influence on the regulation of thymic endocrine secretion.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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