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. 1981 Dec;46(3):493–498.

Studies on visceral Leishmania tropica infection in BALB/c mice. I. Clinical features and cellular changes.

J Djoko-Tamnou, C Leclerc, F Modabber, L Chedid
PMCID: PMC1536314  PMID: 7337976

Abstract

The visceral and lethal infection produced in BALB/c mice by Leishmania tropica (major) is accompanied by splenomegaly, anaemia and reversal of albumin-to-globulin ratio. The percentages of both B and T cells are decreased in the spleen. The spleen and lymph nodes become populated with large Ig-, Thy 1.2- 'null' cells. The similarity of some of these parameters with those produced in human kala-azar is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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