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. 1982 Mar;47(3):587–594.

Antigen provocation to the skin, nose and lung, in children with asthma; immediate and dual hypersensitivity reactions.

J F Price, E N Hey, J F Soothill
PMCID: PMC1536441  PMID: 7083633

Abstract

Most (18/21) children with perennial asthma gave dual (immediate and late) responses to bronchial provocation with two of Dermatophagoides pteronyssinus, and either timothy grass pollen or cat fur. Most (19/21) also showed dual responses to skin prick tests, only half (11/21) gave dual responses in the nose, mainly with timothy grass pollen, and these were associated with allergic rhinitis. Only two children gave dual responses in lung, skin and nose to both antigens, and only two gave immediate reactions without late reactions in all positive tests; most showed different patterns of response according to the organ tested or the antigen used for provocation. Our results suggest that local factors may be important in determining the pattern of allergic response in a 'target' organ, and that dual responses are strongly associated with the patient's symptoms.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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