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Clinical and Experimental Immunology logoLink to Clinical and Experimental Immunology
. 1982 Mar;47(3):677–682.

Idiotypic peripheral blood lymphocytes in monoclonal gammopathy

E J E G Bast, B Van Camp, Philippine Reynaert, G Wiringa, R E Ballieux
PMCID: PMC1536443  PMID: 6805989

Abstract

Using two sets of anti-idiotypic antibody reagents (from guinea-pig and rabbit origin), idiotypic peripheral blood lymphocytes (PBL) could be shown in multiple myeloma (MM) patients in relapse, but not in remission. In patients having the benign form of monoclonal gammopathy (BMG), idiotypic lymphocytes were lacking except in some patients which were depicted as a `high risk' group, by a multivariate rating system. If present, idiotypic lymphocytes accounted for 1-4% of PBL.

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Selected References

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