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. 1980 Apr;40(1):193–196.

Cimetidine does not accelerate skin graft rejection in mice.

H P Festen, J H Berden, R A Koene
PMCID: PMC1536940  PMID: 6993076

Abstract

The influence of cimetidine on skin graft rejection was studied in a well defined transplantation model of inbred mice. Four allogeneic transplantation combinations with increasing antigenic disparity and one xenograft combination were studied. Cimetidine (25 mg/kg body weight) was administered intraperitoneally at 8-hr intervals until rejection occurred. No differences in graft survival were observed between cimetidine-treated groups and saline-treated controls in any of the combinations studied.

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Selected References

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