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. 1980 Dec;42(3):554–560.

Electron microscopic demonstration of lesions in target cell membranes associated with antibody-dependent cellular cytotoxicity.

R R Dourmashkin, P Deteix, C B Simone, P Henkart
PMCID: PMC1537145  PMID: 7214742

Abstract

To test the hypothesis that complement-mediated cell lysis and cell-mediated cytotoxicity operate by analogous mechanisms, cell membranes from two antibody-dependent cytotoxicity systems were examined by electron microscopy after negative staining. Ring-shaped membrane lesions generally similar to, but larger than, those previously described for complement lysis were observed. These findings are in agreement with recent measurements of larger functional pores for ADCC than complement.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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