Abstract
Four of 18 patients with common variable immunodeficiency and one of eight patients with selective IgA deficiency had increased proportions of T epsilon cells. Three patients with common variable immunodeficiency and two with selective IgA deficiency had increased numbers of T epsilon cells. Three patients with common variable immunodeficiency had decreased numbers of T epsilon cells. Five of six patients with hyperimmunoglobulinaemia E had high proportions of T epsilon cells; this increase was not related to the elevated IgE levels.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Canonica G. W., Mingari M. C., Melioli G., Colombatti M., Moretta L. Imbalances of T cell subpopulations in patients with atopic diseases and effect of specific immunotherapy. J Immunol. 1979 Dec;123(6):2669–2672. [PubMed] [Google Scholar]
- Chiorazzi N., Fox D. A., Katz D. H. Hapten-specific IgE antibody responses in mice. VII. Conversion of IgE "non-responder" strains to IgE "responders" by elimination of suppressor T cell activity. J Immunol. 1977 Jan;118(1):48–54. [PubMed] [Google Scholar]
- Gonzalez-Molina A., Spiegelberg H. L. A subpopulation of normal human peripheral B lymphcytes that bind IgE. J Clin Invest. 1977 Apr;59(4):616–624. doi: 10.1172/JCI108679. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gupta S., Fernandes G., Nair M., Good R. A. Spontaneous and antibody-dependent cell-mediated cytotoxicity by human T cell subpopulations. Proc Natl Acad Sci U S A. 1978 Oct;75(10):5137–5141. doi: 10.1073/pnas.75.10.5137. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gupta S., Fikrig S., Good R. A. Subpopulations of human T lymphocytes. XIII. T cell subpopulations (T mu and T gamma) in children with bronchial asthma. Int Arch Allergy Appl Immunol. 1980;61(3):293–298. [PubMed] [Google Scholar]
- Gupta S., Good R. A. Markers of human lymphocyte subpopulations in primary immunodeficiency and lymphoproliferative disorders. Semin Hematol. 1980 Jan;17(1):1–29. [PubMed] [Google Scholar]
- Gupta S., Good R. A. Subpopulations of human T lymphocytes. I. Studies in immunodeficient patients. Clin Exp Immunol. 1977 Nov;30(2):222–228. [PMC free article] [PubMed] [Google Scholar]
- Gupta S., Good R. A. Subpopulations of human T lymphocytes. V. T lymphocytes with receptors for immunoglobulin M or G in patients with primary immunodeficiency disorders. Clin Immunol Immunopathol. 1978 Nov;11(3):292–302. doi: 10.1016/0090-1229(78)90053-3. [DOI] [PubMed] [Google Scholar]
- Gupta S., Platsoucas C. D., Good R. A. Receptors for IgA on a subpopulation of human B lymphocytes. Proc Natl Acad Sci U S A. 1979 Aug;76(8):4025–4028. doi: 10.1073/pnas.76.8.4025. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gupta S., Schwartz S. A., Good R. A. Subpopulations of human T lymphocytes. VII. Cellular basis of concanavalin A-induced T cell-mediated suppression of immunoglobulin production by B lymphocytes from normal humans. Cell Immunol. 1979 May;44(2):242–251. doi: 10.1016/0008-8749(79)90002-9. [DOI] [PubMed] [Google Scholar]
- Hayward A. R., Layward L., Lydyard P. M., Moretta L., Dagg M., Lawton A. R. Fc-receptor heterogeneity of human suppressor T cells. J Immunol. 1978 Jul;121(1):1–5. [PubMed] [Google Scholar]
- Hellström U., Spiegelberg H. L. Characterization of human lymphocytes bearing Fc receptors for IgE isolated from blood and lymphoid organs. Scand J Immunol. 1979;9(1):75–86. doi: 10.1111/j.1365-3083.1979.tb02709.x. [DOI] [PubMed] [Google Scholar]
- Katz D. H. The allergic phenotype: manifestation of 'allergic breakthrough' and imbalance in normal 'damping' of IgE antibody production. Immunol Rev. 1978;41:77–108. doi: 10.1111/j.1600-065x.1978.tb01461.x. [DOI] [PubMed] [Google Scholar]
- Moretta L., Webb S. R., Grossi C. E., Lydyard P. M., Cooper M. D. Functional analysis of two human T-cell subpopulations: help and suppression of B-cell responses by T cells bearing receptors for IgM or IgG. J Exp Med. 1977 Jul 1;146(1):184–200. doi: 10.1084/jem.146.1.184. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tada T. Regulation of reaginic antibody formation in animals. Prog Allergy. 1975;19:122–194. [PubMed] [Google Scholar]
- Trompeter R. S., Layward L., Hayward A. R. Primary and secondary abnormalities of T cell subpopulations. Clin Exp Immunol. 1978 Dec;34(3):388–392. [PMC free article] [PubMed] [Google Scholar]
- Yodoi J., Ishizaka K. Lymphocytes bearing Fc receptors for IgE. I. Presence of human and rat T lymphocytes with Fc epsilon receptors. J Immunol. 1979 Jun;122(6):2577–2583. [PubMed] [Google Scholar]
- Yodoi J., Ishizaka T., Ishizaka K. Lymphocytes bearing Fc receptors for IgE. II. Induction of Fcepsilon-receptor bearing rat lymphocytes by IgE. J Immunol. 1979 Jul;123(1):455–462. [PubMed] [Google Scholar]