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. 1981 Feb;43(2):291–297.

Increased numbers of cells with suppressor T cell phenotype in the peripheral blood of patients with infectious mononucleosis.

D H Crawford, P Brickell, N Tidman, I McConnell, A V Hoffbrand, G Janossy
PMCID: PMC1537280  PMID: 6456093

Abstract

Peripheral blood cells from six patients with acute infectious mononucleosis were studied by two-colour immunofluorescence using antibodies to human T cells, inducer and suppressor-cytotoxic T cell subsets and Ia-like antigens. The absolute number of T cells with the suppressor-cytotoxic phenotype was substantially increased in each case; many of these cells also expressed Ia-like antigens and had the morphology of the large atypical cells characteristic of infectious mononucleosis. These activated suppressor T cells of infectious mononucleosis may therefore represent a control mechanism to prevent viral-induced proliferation of B cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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