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. 1979 Aug;37(2):239–246.

Experimental immune glomerulonephritis induced in the rabbit with streptococcal vaccine.

B Bellon, J Kuhn, K Ayed, J F Girard, P Druet
PMCID: PMC1537805  PMID: 387310

Abstract

Heavy C3 glomerular deposits were observed in rabbits injected intravenously with C5 streptococcal vaccine. Immunoglobulin deposits appeared later in a few rabbits. Although some data favour the presence of circulating immune complexes during the course of this glomerulonephritis, no evidence for their initiating role could be demonstrated. Streptococcal components are known to activate the alternative pathway of complement. It is suggested that complexes made of streptococcal components and activated C3 might deposit in glomerular tufts.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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