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. 1980 Feb;39(2):455–460.

Interaction between fibroblasts, lipoproteins and three antilipoproteins IgA kappa.

M F Baudet, C Dachet, J L Beaumont
PMCID: PMC1538076  PMID: 6771077

Abstract

Human low density lipoproteins are metabolized by cultured human fibroblasts, through a specific metabolic pathway, which entails the regulation of intracellular cholesterol synthesis. When anti-lipoprotein IgA coming from patients with myeloma, mixed hyperlipidaemia and xanthomatosis were introduced into the system, we observed a decrease of the protein degradation of the LDL molecule, and a disappearance of the regulation of intracellular cholesterol synthesis. In the same system, an anti-lipoprotein IgA from a case of myeloma with mixed hyperlipidaemia, but without xanthomatosis, or control IgG and IgA were inactive and did not modify the LDL pathway.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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