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. 1975 Jul;21(1):32–38.

Thymus transplantation. Reconstitution of cellular immunity in a four-year-old patient with T-cell deficiency.

L Businco, E Rezza, G Giunchi, F Aiuti
PMCID: PMC1538249  PMID: 171111

Abstract

The case is reported of a 4-year-old girl affected with recurrent infections; anaemia, thrombocytopenia, haemorrhages and hepatosplenomegaly. Immunological investigations revealed a defect in cellular immunity related to the thymus-dependent system, hypergammaglobulinaemia (especially of class IgE), and very high titres of antibodies against Epstein-Barr virus (EBV). After foetal thymus transplantation, correction of the immunological defect and significant clinical improvement were noted, as well as a decrease of IgE and EBV antibody titres.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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