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. 1975 Dec;22(3):539–545.

Suppression of experimental allergic encephalomyelitis in guinea-pigs with poly-L-lysine.

E Chelmicka-Szorc, B G Arnason
PMCID: PMC1538429  PMID: 5213

Abstract

Poly-L-lysin (PLL) given subcutaneously in a dose of 3 mg/day suppresses experimental allergic encephalomyelitis in guinea-pigs. The suppressive effect of PLL can still be demonstrated when administration is begun 8 days post-immunization. The effect is disease- and species-specific since PLL (3 mg/day) does not suppress experimental allergic orchitis in guinea-pigs, nor does it suppress EAE in rats (1-5 mg/day). PLL (0-2 mg/day) does not decrease the severity of graft-versus-host disease (GVH) in mice as judged by the spleen/body weight assay.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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