Abstract
The frequency of Fc-receptor positive B lymphocytes in human blood was investigated. Under the conditions used heat-aggregated gammaglobulin binding and EA(ox)-rosette formation labelled the same lymphocyte populations. Using various techniques, double marking and cell separations the proportion of Fc-receptor positive cells within the surface Ig carrying population was estimated to be between 11-8 and 36-2%. The proportion of SIg carrying cells within the population forming EA-rosettes was between 11 and 26-4%. This represents extreme values due to known technical circumstances.
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- Brain P., Marston R. H. Rosette formation by human T and B lymphocytes. Eur J Immunol. 1973 Jan;3(1):6–9. doi: 10.1002/eji.1830030103. [DOI] [PubMed] [Google Scholar]
- Brown G., Greaves M. F. Cell surface markers for human T and B lymphocytes. Eur J Immunol. 1974 Apr;4(4):302–310. doi: 10.1002/eji.1830040414. [DOI] [PubMed] [Google Scholar]
- Cornain S., Carnaud C., Silverman D., Klein E., Rajewsky M. F. Spleen-cell reactivity against transplanted neurogenic rat tumors induced by ethylnitrosourea: uncovering of tumor specificity after removal of complement-receptor-bearing lymphocytes. Int J Cancer. 1975 Aug 15;16(2):301–311. doi: 10.1002/ijc.2910160213. [DOI] [PubMed] [Google Scholar]
- Dickler H. B., Kunkel H. G. Interaction of aggregated -globulin with B lymphocytes. J Exp Med. 1972 Jul 1;136(1):191–196. doi: 10.1084/jem.136.1.191. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dickler H. B. Studies of the human lymphocyte receptor for heat-aggregated or antigen-complexed immunoglobulin. J Exp Med. 1974 Aug 1;140(2):508–522. doi: 10.1084/jem.140.2.508. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Froland S. S., Natvig J. B., Michaelsen T. E. Binding of aggregated IgG BY HUMAN B lymphocytes independent of Fc receptors. Scand J Immunol. 1974;3(3):375–380. doi: 10.1111/j.1365-3083.1974.tb01268.x. [DOI] [PubMed] [Google Scholar]
- Froland S. S., Wisloff F., Michaelsen T. E. Human lymphocytes with receptors for IgG. A population of cells distinct from T- and B-lymphocytes. Int Arch Allergy Appl Immunol. 1974;47(1):124–138. doi: 10.1159/000231207. [DOI] [PubMed] [Google Scholar]
- Hallberg T., Gurner B. W., Coombs R. R. Opsonic adherence of sensitized ox red cells to human lymphocytes as measured by rosette formation. Int Arch Allergy Appl Immunol. 1973;44(4):500–513. doi: 10.1159/000230956. [DOI] [PubMed] [Google Scholar]
- Horwitz D. A., Lobo P. I. Characterizaiton of two populations of human lymphocytes bearing easily detectable surface immunoglobulin. J Clin Invest. 1975 Dec;56(6):1464–1472. doi: 10.1172/JCI108227. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jondal M., Klein G. Surface markers on human B and T lymphocytes. II. Presence of Epstein-Barr virus receptors on B lymphocytes. J Exp Med. 1973 Dec 1;138(6):1365–1378. doi: 10.1084/jem.138.6.1365. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jondal M. Surface markers on human B and T lymphocytes. IV. Distribution of surface markers on resting and blast-transformed lymphocytes. Scand J Immunol. 1974;3(6):739–747. doi: 10.1111/j.1365-3083.1974.tb01309.x. [DOI] [PubMed] [Google Scholar]
- Julius M. H., Simpson E., Herzenberg L. A. A rapid method for the isolation of functional thymus-derived murine lymphocytes. Eur J Immunol. 1973 Oct;3(10):645–649. doi: 10.1002/eji.1830031011. [DOI] [PubMed] [Google Scholar]
- Kurnick J. T., Grey H. M. Relationship between immunoglobulin-bearing lymphocytes and cells reactive with sensitized human erythrocytes. J Immunol. 1975 Jul;115(1):305–307. [PubMed] [Google Scholar]
- Lobo P. I., Westervelt F. B., Horwitz D. A. Identification of two populations of immunoglobulin-bearing lymphocytes in man. J Immunol. 1975 Jan;114(1 Pt 1):116–119. [PubMed] [Google Scholar]
- Samarut C., Brochier J., Revillard J. P. Distribution of cells binding erythrocyte-antibody (EA) complexes in human lymphoid populations. Scand J Immunol. 1976;5(3):221–231. doi: 10.1111/j.1365-3083.1976.tb00273.x. [DOI] [PubMed] [Google Scholar]
- Sandilands G., Gray K., Cooney A., Froebel K., Anderson J. R. Human lymphocyte sub-populations and K cells. Int Arch Allergy Appl Immunol. 1976;50(4):416–426. doi: 10.1159/000231531. [DOI] [PubMed] [Google Scholar]