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. 1977 Mar;27(3):464–468.

An inhibitor of lymphocyte proliferation and lymphokine production released by unstimulated foetal monocytes.

R L Wolf, R Lominitzer, A R Rabson
PMCID: PMC1540942  PMID: 862232

Abstract

Supernatants obtained from 3-day cultures of cord blood monocytes inhibited normal lymphocyte activation by either PHA or in a two-way MLC. Both lymphocyte transformation and lymphokine production was significantly inhibited by these supernatants but not by those derived from adult mononuclear cell cultures. The inhibitory material produced by foetal monocytes was dialysable and was non-cytotoxic to target cells. It is postulated that this factor contributes to the depressed maternal cell-mediated immune response observed in pregnancy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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