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. 1977 Jun;28(3):542–545.

Spontaneous lymphocyte transformation in chronic lymphocytic leukaemia.

G Semenzato, G Amadori, F Tosato, G Gasparotto
PMCID: PMC1541010  PMID: 302167

Abstract

In ten patients with CLL and in eight controls T lymphocytes were separated out by the rosetting method. The in vitro reactivity of these cells and of unseparated lymphocytes was studied in cultures without stimulants. A net increase of spontaneous lymphocyte transformation was found in the populations enriched with T cells in patients with CLL with respect to analogous populations in the controls. This increase is interpreted as a cell-mediated immunological reaction and due to T-cell sensitization towards the neoplastic B cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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