Abstract
With the aid of insolubilized immunoadsorbents made with glycoproteins, extracted from cow red blood cells (RBC), and with guinea-pig kidney tissue, heterophile antibody populations of the Paul--Bunnell type and the Forssman type were eluted from infectious mononucleosis sera. Two Paul--Bunnell-type antibody populations were separated on the basis of their affinity for cow RBC antigens. The lymphocytotoxic antibodies in the infectious mononucleosis sera were eluted among the low-affinity Paul--Bunnell antibodies.
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Selected References
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- Axén R., Porath J., Ernback S. Chemical coupling of peptides and proteins to polysaccharides by means of cyanogen halides. Nature. 1967 Jun 24;214(5095):1302–1304. doi: 10.1038/2141302a0. [DOI] [PubMed] [Google Scholar]
- Bailey G. H., Raffel S. HEMOLYTIC ANTIBODIES FOR SHEEP AND OX ERYTHROCYTES IN INFECTIOUS MONONUCLEOSIS. J Clin Invest. 1935 Mar;14(2):228–244. doi: 10.1172/JCI100671. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Capra J. D., Dowling P., Cook S., Kunkel H. G. An incomplete cold-reactive gamma G antibody with i specificity in infectious mononucleosis. Vox Sang. 1969 Jan;16(1):10–17. doi: 10.1111/j.1423-0410.1969.tb04711.x. [DOI] [PubMed] [Google Scholar]
- Feizi T., Kabat E. A. Immunochemical studies on blood groups. LVI. Purification of glycoproteins with different I determinants from hydatid cyst fluid and from human milk on insoluble anti-I immunoadsorbents. J Immunol. 1974 Jan;112(1):145–150. [PubMed] [Google Scholar]
- Feizi T., Monger E. Microtitration of serum cold agglutinins. Transfusion. 1970 Jan-Feb;10(1):33–35. doi: 10.1111/j.1537-2995.1970.tb00700.x. [DOI] [PubMed] [Google Scholar]
- Fletcher M. A., Lo T. M. Immunochemical studies of infectious mononucleosis. III. Isolation and characterization of heterophile antibodies. Clin Exp Immunol. 1974 Apr;16(4):607–614. [PMC free article] [PubMed] [Google Scholar]
- Fletcher M. A., Woolfolk B. J. Immunochemical studies on infectious mononucleosis. I. Isolation and characterization of heterophile antigens from hemoglobin-free stroma. J Immunol. 1971 Sep;107(3):842–853. [PubMed] [Google Scholar]
- HOLBOROW E. J., ASHERSON G. L., JOHNSON G. D., BARNES R. D., CARMICHAEL D. S. Antinuclear factor and other antibodies in blood and liver diseases. Br Med J. 1963 Mar 9;1(5331):656–658. doi: 10.1136/bmj.1.5331.656. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Henle G., Henle W., Diehl V. Relation of Burkitt's tumor-associated herpes-ytpe virus to infectious mononucleosis. Proc Natl Acad Sci U S A. 1968 Jan;59(1):94–101. doi: 10.1073/pnas.59.1.94. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Henle W., Henle G. E., Horwitz C. A. Epstein-Barr virus specific diagnostic tests in infectious mononucleosis. Hum Pathol. 1974 Sep;5(5):551–565. doi: 10.1016/s0046-8177(74)80006-7. [DOI] [PubMed] [Google Scholar]
- Holborow E. J., Hemsted E. H., Mead S. V. Smooth muscle autoantibodies in infectious mononucleosis. Br Med J. 1973 Aug 11;3(5875):323–325. doi: 10.1136/bmj.3.5875.323. [DOI] [PMC free article] [PubMed] [Google Scholar]
- JENKINS W. J., KOSTER H. G., MARSH W. L., CARTER R. L. INFECTIOUS MONONUCLEOSIS: AN UNSUSPECTED SOURCE ON ANTI-I. Br J Haematol. 1965 Jul;11:480–483. doi: 10.1111/j.1365-2141.1965.tb06611.x. [DOI] [PubMed] [Google Scholar]
- Janossy G., Gomez De La Concha E., Waxdal M. J., Platts-Mills T. The effects of purified mitogenic proteins (Pa-1 and Pa-2) from pokeweed on human T and B lymphocytes in vitro. Clin Exp Immunol. 1976 Oct;26(1):108–117. [PMC free article] [PubMed] [Google Scholar]
- Julius M. H., Simpson E., Herzenberg L. A. A rapid method for the isolation of functional thymus-derived murine lymphocytes. Eur J Immunol. 1973 Oct;3(10):645–649. doi: 10.1002/eji.1830031011. [DOI] [PubMed] [Google Scholar]
- Kaplan M. E. Cryoglobulinemia in infectious mononucleosis: quantitation and characterization of the cryoproeins. J Lab Clin Med. 1968 May;71(5):754–765. [PubMed] [Google Scholar]
- Kaplan M. E., Tan E. M. Antinuclear antibodies in infectious mononucleosis. Lancet. 1968 Mar 16;1(7542):561–563. doi: 10.1016/s0140-6736(68)92831-6. [DOI] [PubMed] [Google Scholar]
- LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
- Lowenthal R. M., McLauchlan S. L., Tyrrell D. A. Human antigen for the Paul-Bunnell antibody. Nat New Biol. 1973 Jul 25;244(134):109–111. doi: 10.1038/newbio244109a0. [DOI] [PubMed] [Google Scholar]
- Malavé I., Milgrom F. Heterophile antigen detected by infectious mononucleosis sera on lymphoid cells. Int Arch Allergy Appl Immunol. 1973;44(5):601–610. doi: 10.1159/000230964. [DOI] [PubMed] [Google Scholar]
- Milgrom F., Kano K., Fjelde A. Studies on heterophile antigen in lymphoma and leukemia spleens by means of absorption of infectious mononucleosis sera. Int Arch Allergy Appl Immunol. 1973;45(4):631–637. doi: 10.1159/000231106. [DOI] [PubMed] [Google Scholar]
- Miller G. Epstein-Barr herpesvirus and infectious mononucleosis. Prog Med Virol. 1975;20:84–112. [PubMed] [Google Scholar]
- Niederman J. C., McCollum R. W., Henle G., Henle W. Infectious mononucleosis. Clinical manifestations in relation to EB virus antibodies. JAMA. 1968 Jan 15;203(3):205–209. doi: 10.1001/jama.203.3.205. [DOI] [PubMed] [Google Scholar]
- Rogentine G. N., Jr, Plocinik B. A. Carbohydrate inhibition studies of the naturally occurring human antibody to neuraminidase-treated human lymphocytes. J Immunol. 1974 Sep;113(3):848–858. [PubMed] [Google Scholar]
- Rosenberg S. A., Rogentine G. N., Jr Natural human antibodies to "hidden" membrane components. Nat New Biol. 1972 Oct 18;239(94):203–204. doi: 10.1038/newbio239203a0. [DOI] [PubMed] [Google Scholar]
- TOMCSIK J. The serological diagnosis of infectious mononucleosis. Triangle. 1961 Jul;5:114–120. [PubMed] [Google Scholar]
- Thomas D. B. Antibodies specific for human T lymphocytes in cold agglutinin and lymphocytotoxic sera. Eur J Immunol. 1973 Dec;3(12):824–828. doi: 10.1002/eji.1830031216. [DOI] [PubMed] [Google Scholar]
- Thomas D. B. Antibodies to membrane antigen(s) common to thymocytes and a subpopulation of lymphocytes in infectious-mononucleosis sera. Lancet. 1972 Feb 19;1(7747):399–403. doi: 10.1016/s0140-6736(72)90854-9. [DOI] [PubMed] [Google Scholar]
- Wager O., Räsänen J. A., Hagman A., Klemola E. Mixed cryoimmunoglobulinaemia in infectious mononucleois and Cytomegalovirus mononucleosis. Int Arch Allergy Appl Immunol. 1968;34(4):345–361. doi: 10.1159/000230129. [DOI] [PubMed] [Google Scholar]
- Wright B. M., Edwards A. J., Jones V. E. Use of a cell rupturing pump for the preparation of thymocyte subcellular fractions. J Immunol Methods. 1974 Mar;4(2):281–296. doi: 10.1016/0022-1759(74)90071-4. [DOI] [PubMed] [Google Scholar]
- Yoshida K., Nahmias A. Specific heterophile antibody from infectious mononucleosis serum. Proc Soc Exp Biol Med. 1967 Feb;124(2):515–518. doi: 10.3181/00379727-124-31778. [DOI] [PubMed] [Google Scholar]
