Abstract
An increased incidence and severity of interstitial nephritis was produced in F344/fmai rats immunized with E. coli 022 in pertussis vaccine for 12-15 months. Migration of peritoneal exudate cells from immunized animals was inhibited by syngeneic kidney antigens. One out of twenty-eight immunized animals developed anti-TBM antibodies. In this model, interstitial nephritis develops in association with cell-mediated immunity to kidney tissue.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BERENBAUM M. C., KITCH G. M., COPE W. A. Spurious 'autoimmune' reactions in gel-diffusion plates. Nature. 1962 Jan 6;193:81–82. doi: 10.1038/193081a0. [DOI] [PubMed] [Google Scholar]
- Holmgren J., Hanson L. A., Holm S. E., Kauser B. An antigenic relationship between kidney and certain Escherichia coli strains. Int Arch Allergy Appl Immunol. 1971;41(2):463–474. doi: 10.1159/000230540. [DOI] [PubMed] [Google Scholar]
- Ibrahim A. B., Vyas G. N. A simple inexpensive method for demonstrating in vitro leukocyte migration. Vox Sang. 1973 Dec;25(6):552–556. doi: 10.1111/j.1423-0410.1973.tb03551.x. [DOI] [PubMed] [Google Scholar]
- Lehmann J. D., Smith J. W., Miller T. E., Barnett J. A., Sanford J. P. Local immune response in experimental pyelonephritis. J Clin Invest. 1969 Nov;47(11):2541–2550. doi: 10.1172/JCI105936. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Montgomerie J. Z., Kalmanson G. M., Guze L. B. Pyelonephritis: an attempt to demonstrate renal autoimmunity. N Z Med J. 1969 Oct;70(449):244–246. [PubMed] [Google Scholar]
- SUZUKI T., GORZYNSKI E. A., NETER E. SEPARATION BY ETHANOL OF COMMON AND SOMATIC ANTIGENS OF ENTEROBACTERIACEAE. J Bacteriol. 1964 Nov;88:1240–1243. doi: 10.1128/jb.88.5.1240-1243.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]