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. 1987 Oct;70(1):231–237.

The relative roles of genetic and environmental factors in the regulation of erythrocyte C3b receptor (ECR1) numbers in normal individuals.

A Fyfe 1, E R Holme 1, I C McKay 1, A Zoma 1, J Hunter 1, N P Lucie 1, K Whaley 1
PMCID: PMC1542200  PMID: 2961490

Abstract

Erythrocyte C3b receptors (ECR1) have been measured in 122 pairs of twins (60 monozygotic, 62 dizygotic) using an [125I]-labelled monoclonal antibody (E11). The range of ECR1 numbers was wide, 99-4179 sites/cell, with a log-normal distribution around a geometric mean of 837 sites/cell. The intra-pair variance in dizygotic twins was no greater than that in monozygotic twins. These data indicate that ECR1 numerical expression is governed by environmental rather than genetic factors.

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Selected References

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