Abstract
E- cells from three patients with X-linked and three patients with non-familial 'common variable' hypogammaglobulinaemia were stained by indirect immunofluorescence with a panel of B cell specific monoclonal antibodies (anti-Bp95, Bp35 and Bp135). The number of B cells detected with the pan-B cell antibodies was variable between patients. One patient in each group was found to have near normal numbers of circulating B cells although those of the X-linked patient were clearly immature.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Beverley P. C., Callard R. E. Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. Eur J Immunol. 1981 Apr;11(4):329–334. doi: 10.1002/eji.1830110412. [DOI] [PubMed] [Google Scholar]
- Chiao J. W., Ascensáo J., Pahwa S., Pahwa R., Good R. A. An analysis of lymphocytes with both T-cell marker and IgG or complement receptors in patients with X-linked agammaglobulinemia. Clin Immunol Immunopathol. 1976 Sep;6(2):141–148. doi: 10.1016/0090-1229(76)90104-5. [DOI] [PubMed] [Google Scholar]
- Conley M. E. B cells in patients with X-linked agammaglobulinemia. J Immunol. 1985 May;134(5):3070–3074. [PubMed] [Google Scholar]
- Froland S. S., Natvig J. B. Surface-bound immunoglobulin on lymphocytes from normal and immunodeficient humans. Scand J Immunol. 1972;1(1):1–12. doi: 10.1111/j.1365-3083.1972.tb03730.x. [DOI] [PubMed] [Google Scholar]
- Fu S. M., Hurley J. N., McCune J. M., Kunkel H. G., Good R. A. Pre-B cells and other possible precursor lymphoid cell lines derived from patients with X-linked agammaglobulinemia. J Exp Med. 1980 Dec 1;152(6):1519–1526. doi: 10.1084/jem.152.6.1519. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hogg N., MacDonald S., Slusarenko M., Beverley P. C. Monoclonal antibodies specific for human monocytes, granulocytes and endothelium. Immunology. 1984 Dec;53(4):753–767. [PMC free article] [PubMed] [Google Scholar]
- Horwitz D. A., Webster A. D., Newton C. B and L lymphocytes in primary hypogammaglobulinaemia. Lancet. 1977 Oct 15;2(8042):823–824. doi: 10.1016/s0140-6736(77)90758-9. [DOI] [PubMed] [Google Scholar]
- Levitt D., Ochs H., Wedgwood R. J. Epstein-Barr virus-induced lymphoblastoid cell lines derived from the peripheral blood of patients with X-linked agammaglobulinemia can secrete IgM. J Clin Immunol. 1984 Mar;4(2):143–150. doi: 10.1007/BF00915048. [DOI] [PubMed] [Google Scholar]
- Nadler L. M., Anderson K. C., Marti G., Bates M., Park E., Daley J. F., Schlossman S. F. B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes. J Immunol. 1983 Jul;131(1):244–250. [PubMed] [Google Scholar]
- Preud'Homme J. L., Griscelli C., Seligmann M. Immunoglobulins on the surface of lymphocytes in fifty patients with primary immunodeficiency diseases. Clin Immunol Immunopathol. 1973 Jan;1(2):241–256. doi: 10.1016/0090-1229(73)90025-1. [DOI] [PubMed] [Google Scholar]
- Schwaber J., Lazarus H., Rosen F. S. Restricted classes of immunoglobulin produced by a lymphoid cell line from a patient with agammaglobulinemia. Proc Natl Acad Sci U S A. 1978 May;75(5):2421–2423. doi: 10.1073/pnas.75.5.2421. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stashenko P., Nadler L. M., Hardy R., Schlossman S. F. Characterization of a human B lymphocyte-specific antigen. J Immunol. 1980 Oct;125(4):1678–1685. [PubMed] [Google Scholar]
- Tsuchiya S., Konno T., Tada K., Ono Y. Epstein-Barr virus-induced lymphoblastoid cell lines from patients with primary immunodeficiency diseases. Scand J Immunol. 1980;11(2):155–162. doi: 10.1111/j.1365-3083.1980.tb00221.x. [DOI] [PubMed] [Google Scholar]