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Clinical and Experimental Immunology logoLink to Clinical and Experimental Immunology
. 1986 Oct;66(1):241–247.

Agglutination of intravenous lipid emulsion ('Intralipid') and plasma lipoproteins by C-reactive protein.

I R Rowe, A K Soutar, M B Pepys
PMCID: PMC1542672  PMID: 3100118

Abstract

Isolated human C-reactive protein (CRP), or CRP in acute phase serum, produced in-vitro agglutination ('creaming') of the intravenously administered lipid suspension 'Intralipid'. CRP also produced similar agglutination of isolated normal very low density lipoproteins (VLDL). Agglutination in both cases was calcium-dependent and inhibitable by phosphoryl choline. These findings have important implications for patients receiving intravenous lipid suspensions and may be relevant to the pathogenesis of the fat embolism syndrome following trauma.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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